Molecular Formula | C27H40O4 |
Molar Mass | 428.61 |
Density | 1.19±0.1 g/cm3 (20 ºC 760 Torr) |
Melting Point | 196~198℃ |
Boling Point | 566.6±50.0 °C(Predicted) |
Specific Rotation(α) | -118 (c, 0.24 in CHCl3) |
Solubility | Insuluble (5.1E-3 g/L) (25 °C) |
Appearance | White needle crystal |
pKa | 14.55±0.70(Predicted) |
Storage Condition | 2-8℃ |
MDL | MFCD00210534 |
Physical and Chemical Properties | White needle-like crystal, soluble in methanol, ethanol, DMSO and other organic solvents, from the false leaf tree. |
HS Code | 29329990 |
Application | dry root of Ophiopogon japonicus, sweet, slightly bitter, returning to the heart, lung, stomach, nourishing Yin and fluid, runfei Qingxin and other effects, commonly used in the treatment of lung dryness Dry Cough, Yin tuberculosis, sore throat, sore throat, thirst and other diseases. The chemical constituents of Ophiopogon japonicus mainly include saponins, flavonoids, amino acids, polysaccharides and volatile oil. Ophiopogon japonicus steroidal saponin is the main active ingredient of Ophiopogon japonicus, and neosaponin is the key index for the quality control of its medicinal materials, which is the Chinese Pharmacopoeia (2015 Edition). Chemical control for quality inspection of radix ophiopogonis. |
biological activity | neorus cogenin is a natural sapogenin isolated from R. rhizoma. Neorus cogenin is a potent and high-affinity agonist of RAR-related orphan receptor alpha (RORα or nuclear receptor NR1F1). |
Target | Value |
Usage | neoglucosapenin has anti-cancer and hepatoprotective effects. for content determination/identification/pharmacological experiments, etc |