Nintedanib-002

Nintedanib-002 - Names and Identifiers

Name	Methyl 1-acetyl-2-oxoindoline-6-carboxylate
Synonyms	Nintedanib-002 Nintedanib impurity 1 Methyl 1-acetyl-2-oxoindoline-6-carboxylate methyl 1-acetyl-2-oxo-3H-indole-6-carboxylate 1-Acetyl-2,3-dihydro-2-oxo-1H-indole-6-carboxylic acid methyl ester 1-acetyl-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester 1H-Indole-6-carboxylic acid, 1-acetyl-2,3-dihydro-2-oxo-, methyl ester
CAS	676326-36-6

Nintedanib-002 - Physico-chemical Properties

Molecular Formula	C12H11NO4
Molar Mass	233
Density	1.330
Boling Point	489.5±45.0 °C(Predicted)
pKa	-1.94±0.20(Predicted)
Storage Condition	2-8℃
Use	This product is for scientific research only and shall not be used for other purposes.

Nintedanib-002 - Upstream Downstream Industry

Raw Materials	Methyl 2-oxoindole-6-carboxylate Acetic anhydride
Downstream Products	(E)-Methyl 1-acetyl-3-(Methoxy(phenyl)Methylene)-2-oxoindoline-6-carboxylate

Nintedanib-002 - Introduction

Methyl is an organic compound with the chemical formula C12H11NO4. The following is a detailed description of the properties, uses, preparation and safety information of the compound:

Nature:
Methyl L is a white to pale yellow crystalline solid. It is stable at room temperature, but may decompose at high temperatures. It has a strong bitter and pungent odor.

Use:
Methyl L is an important organic synthesis intermediate. It is widely used in the fields of drug synthesis, Pesticide Synthesis and dye synthesis. Its derivatives are widely used in the field of medicine, such as anti-tumor drugs, antiviral drugs and antibacterial drugs.

Method:
There are many ways to prepare Methyl. One common method of preparation is to synthesize the compound by an oxidation reaction. The specific method is that the indolone and methyl acetate are oxidized under alkaline conditions to generate the target product.

Safety Information:
Methyl is generally stable and safe under normal conditions of use. However, it may cause irritation to the eyes, skin and respiratory tract. Therefore, it is necessary to wear appropriate personal protective equipment, such as gloves, protective glasses and breathing masks. In the event of accidental exposure to the compound, the affected area should be flushed immediately with clean water and medical assistance should be sought promptly.

Last Update：2024-04-09 20:45:29

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