Name | 1,9-Nonanediol |
Synonyms | Nonanediol 1,9-NONANEDIOL 1,9-Nonanediol α,ω-nonanediol nonane-1,9-diol 1,9-Dihydroxynonane 1,9-DIHYDROXYNONANE TIMTEC-BB SBB008482 Nonamethylene glycol NONAMETHYLENE GLYCOL alpha,OMEGA-Nonanediol |
CAS | 3937-56-2 |
EINECS | 223-517-5 |
InChI | InChI=1/C9H20O2/c10-8-6-4-2-1-3-5-7-9-11/h10-11H,1-9H2 |
InChIKey | ALVZNPYWJMLXKV-UHFFFAOYSA-N |
Molecular Formula | C9H20O2 |
Molar Mass | 160.25 |
Density | 0.918 |
Melting Point | 45-47 °C (lit.) |
Boling Point | 177 °C/15 mmHg (lit.) |
Flash Point | >230°F |
Water Solubility | 5.7g/L at 20℃ |
Solubility | Soluble in methanol. |
Vapor Presure | 0.004Pa at 20℃ |
Appearance | White crystal |
Color | White |
BRN | 1737531 |
pKa | 14.89±0.10(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.4571 (estimate) |
MDL | MFCD00002991 |
Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
WGK Germany | 2 |
TSCA | Yes |
HS Code | 29053990 |
LogP | 1.69 at 20.8℃ |
NIST chemical information | Information provided by: webbook.nist.gov (external link) |
EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
Introduction | 1,9-nonanediol is an important organic glycol, an organic raw material with a wide range of uses, in the organic synthesis industry, It is the basic raw material; it can also be used to produce lubricants and plasticizers; it can also be used in medicine and other aspects; it can be used in liquid crystal materials, degradable functional polymer materials; production of spices, lubricants, inks, coatings, cosmetics, plasticizers and various additives. It can also be used for the synthesis of various organic intermediates. |
application | 1,9-nonanediol can react with organic acids, isocyanates, and anhydrides to form different types of derivatives. The modified synthesized low melting point and biodegradable polyester is used for food packaging, high-grade fibers, and electrical insulation materials; the synthesized high-performance polyurethane elastomer has excellent crystallinity and high mechanical strength, and is used for the production of rubber and elastic fibers, Artificial leather auto parts; it can also be used as polyester plasticizer, with high volatility resistance, low temperature resistance, water resistance and oil resistance. |
Synthesis method | Add samarium iodide (II)(THF solution, usually 6 equivalents) to acid (pure), then add amine (usually 18 or 36 equivalents) and water (usually 18 or 36 equivalents) in an inert atmosphere, and stir vigorously at room temperature. After a specified time (usually 2-5 h), the excess SmI2 is oxidized by bubbling air through the reaction mixture. The reaction mixture was diluted with CH2Cl2 (30 mL) and HCl (1 N, 30 mL). The water layer is extracted with CH2Cl2 (3x30 mL), the organic layer is combined, dried with Na2SO4, filtered and concentrated. The crude product was purified by short plug silica gel flash chromatography. Unless otherwise stated, all yields refer to individual yields. Nonane -1,9-diol (Table 2, Item 7) According to the general procedure method A, nonane acid (0.10 mmol), samarium iodide (II) (1.2 mmol), water (7.2 mmol) and triethylamine (7.2 mmol) react under rt for 18 hours, and the target compound 1 is obtained by chromatography (1/10-1/1 ethyl acetate/hexane), 9-nonanediol with a yield of 88%. |