Nsc293361 - Names and Identifiers
Nsc293361 - Physico-chemical Properties
Molecular Formula | C17H17N3O4
|
Molar Mass | 327.338 |
Density | 1.24g/cm3 |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
Refractive Index | 1.586 |
Nsc293361 - Introduction
N,N-bis (benzyloxycarbonyl) guanidine, also known as DBN, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
N,N-bis (benzyloxycarbonyl) guanidine is a colorless to pale yellow crystal, soluble in some organic solvents such as ethanol, acetone and dichloromethane, insoluble in water. It has high thermal stability and low toxicity.
Use:
N,N-bis (benzyloxycarbonyl) guanidine is mainly used as a weak base catalyst in organic synthesis. It is commonly used in a variety of reactions, including esterification, acylation, condensation, and nucleophilic substitution. It can also be used as an acid scavenger, ligand and dehydrating agent for hydroxides.
Preparation Method:
N,N-bis (benzyloxycarbonyl) guanidine can be prepared by reacting benzylamine with dimethylformamide. First, benzylamine and dimethylformamide were placed in a reaction flask, and the reaction was stirred at room temperature for a period of time. Subsequently, the resulting mixture is subjected to crystallization or rotary evaporation to obtain N,N-bis (benzyloxycarbonyl) guanidine.
Safety Information:
N,N-bis (benzyloxycarbonyl) guanidine is relatively safe under normal conditions of use, but the following matters still need to be noted:
1. Use appropriate personal protective equipment, such as lab gloves, goggles and lab clothes.
2. avoid inhaling its dust and gas. It should be operated in a well-ventilated place to prevent its vapor accumulation.
3. Avoid contact with strong oxidants and acidic substances to avoid dangerous reactions.
4. storage should be sealed, away from the fire and flammable materials.
Last Update:2024-04-09 21:01:54