Nt-((Benzyloxy)carbonyl)-Na-(tert-butoxycarbonyl)-L-histidine
Boc-His(Z)-OH
CAS: 50305-43-6
Molecular Formula: C19H23N3O6
Nt-((Benzyloxy)carbonyl)-Na-(tert-butoxycarbonyl)-L-histidine - Names and Identifiers
Nt-((Benzyloxy)carbonyl)-Na-(tert-butoxycarbonyl)-L-histidine - Physico-chemical Properties
| Molecular Formula | C19H23N3O6 |
| Molar Mass | 389.4 |
| Density | 1.27±0.1 g/cm3(Predicted) |
| pKa | 12.90±0.46(Predicted) |
| Storage Condition | Sealed in dry,Store in freezer, under -20°C |
Nt-((Benzyloxy)carbonyl)-Na-(tert-butoxycarbonyl)-L-histidine - Introduction
Boc-His(Z)-OH is an amino acid derivative, also known as Boc-His(Z)-OH. It has the following properties:
1. appearance: the common form is white or white crystalline powder.
2. Solubility: It can be dissolved in common organic solvents, such as dimethyl sulfoxide (DMSO) and dimethyl formamide (DMF).
3. Boc protecting group and Cbz protecting group: N-Boc and N'-Cbz are commonly used protecting groups, which can protect the nitrogen atom in amino acids to prevent side reactions during the synthesis process.
Boc-His(Z)-OH is mainly used in the field of organic synthesis, as an intermediate for the preparation of more complex compounds and biologically active substances. It is commonly used as a starting material in polypeptide synthesis. Since it is a chiral amino acid, it can be used to synthesize peptides or proteins with a specific chirality.
The preparation of Boc-His(Z)-OH can usually be carried out by the following steps:
1. first, the N-protecting group (such as Boc protecting group) is introduced into the amino group of histidine;
2. Subsequently, a Cbz protecting group was introduced into the carboxyl group of histidine.
Laboratory safety procedures are followed during synthesis to ensure safe compound preparation. Boc-His the safety information of (Z)-OH is limited, proper handling and storage methods should be followed when using, and care should be taken to prevent contact with skin and inhalation. At the same time, according to the characteristics of chemicals, the disposal of waste should comply with relevant regulations. It is best to operate in an organic synthesis laboratory or in a professionally directed environment.
1. appearance: the common form is white or white crystalline powder.
2. Solubility: It can be dissolved in common organic solvents, such as dimethyl sulfoxide (DMSO) and dimethyl formamide (DMF).
3. Boc protecting group and Cbz protecting group: N-Boc and N'-Cbz are commonly used protecting groups, which can protect the nitrogen atom in amino acids to prevent side reactions during the synthesis process.
Boc-His(Z)-OH is mainly used in the field of organic synthesis, as an intermediate for the preparation of more complex compounds and biologically active substances. It is commonly used as a starting material in polypeptide synthesis. Since it is a chiral amino acid, it can be used to synthesize peptides or proteins with a specific chirality.
The preparation of Boc-His(Z)-OH can usually be carried out by the following steps:
1. first, the N-protecting group (such as Boc protecting group) is introduced into the amino group of histidine;
2. Subsequently, a Cbz protecting group was introduced into the carboxyl group of histidine.
Laboratory safety procedures are followed during synthesis to ensure safe compound preparation. Boc-His the safety information of (Z)-OH is limited, proper handling and storage methods should be followed when using, and care should be taken to prevent contact with skin and inhalation. At the same time, according to the characteristics of chemicals, the disposal of waste should comply with relevant regulations. It is best to operate in an organic synthesis laboratory or in a professionally directed environment.
Last Update：2024-04-09 21:32:41
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CAS: 50305-43-6
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CAS: 50305-43-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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