O-(Z,Z,Z,Z-heptatriaconta-6,9,26,29-tetraen-19-yl)-4-(N,N-dimethylamino) - Names and Identifiers
Name | DLin-M-C3-DMA
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Synonyms | DLINMC3DMA DLin-M-C3-DMA D-LIN-MC3-DMA D-Lin-MC3-DMA D-LIN-MC-3-DMA D-Lin-MC3-DMA (MC3) dilinoleylmethyl 4-(dimethylamino)butanoate O-(Z,Z,Z,Z-heptatriaconta-6,9,26,29-tetraen-19-yl)-4-(N,N-dimethylamino) (6Z,9Z,28Z,31Z)-heptatriaconta-6,9,28,31-tetraen-19-yl 4-(dimethylamino)butanoate (6Z,9Z,28Z,31Z)-heptatriacont-6,9,28,31-tetraene-19-yl 4-(dimethylamino)butanoate Butanoic acid, 4-(dimethylamino)-, (10Z,13Z)-1-(9Z,12Z)-9,12-octadecadien-1-yl-10,13-nonadecadien-1-yl ester
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CAS | 1224606-06-7
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O-(Z,Z,Z,Z-heptatriaconta-6,9,26,29-tetraen-19-yl)-4-(N,N-dimethylamino) - Physico-chemical Properties
Molecular Formula | C43H79NO2
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Molar Mass | 642.09 |
Density | 0.886±0.06 g/cm3(Predicted) |
Boling Point | 670.2±43.0 °C(Predicted) |
Solubility | DMSO : ≥ 43.33 mg/mL (67.48 mM) ; Ethanol : 16.67 mg/mL (25.96 mM; Need ultrasonic) |
pKa | 9.37±0.28(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
Physical and Chemical Properties | Bioactive D-Lin-MC3-DMA (MC3, DLin-MC3-DMA) is an effective and ionizable cationic liposome. D-Lin-MC3-DMA is used to deliver siRNA in vivo. |
Use | The chemical name of the DLIN-M-C3-DMA is 4-(N,N-dimethylamine) butyric acid -6,9,28, 31-tetraene-19-trimetanol ester, which can be used to prepare liposome preparations. Liposome preparations include complementary double positive lipids, phospholipids and long-acting lipids. Complementary double positive lipids include: the first positive lipid and the second positive lipid. DLIN-M-C3-DMA can be used as the first positive lipid. |
O-(Z,Z,Z,Z-heptatriaconta-6,9,26,29-tetraen-19-yl)-4-(N,N-dimethylamino) - Upstream Downstream Industry
Raw Materials | 6,9,28,31-Heptatriacontatetraen-19-ol, (6Z,9Z,28Z,31Z)- 4-DIMETHYLAMINOBUTYRIC ACID HYDROCHLORIDE CIS,CIS-9,12-OCTADECADIENOL 9,12-Octadecadien-1-ol, methanesulfonate, (9Z,12Z)- 4-(Dimethylamino)butanoic acid
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O-(Z,Z,Z,Z-heptatriaconta-6,9,26,29-tetraen-19-yl)-4-(N,N-dimethylamino) - Preparation solution concentration reference
| 1mg | 5mg | 10mg |
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1 mM | 1.557 ml | 7.787 ml | 15.574 ml |
5 mM | 0.311 ml | 1.557 ml | 3.115 ml |
10 mM | 0.156 ml | 0.779 ml | 1.557 ml |
5 mM | 0.031 ml | 0.156 ml | 0.311 ml |
Last Update:2024-01-02 23:10:35
O-(Z,Z,Z,Z-heptatriaconta-6,9,26,29-tetraen-19-yl)-4-(N,N-dimethylamino) - Introduction
DLin-M-C3-DMA, also known as DMBAE, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: DMBAE is a colorless liquid
-Molecular formula: C13H25NO2
-Molecular weight: 227.34g/mol
-Melting point:-30 ° C
-Boiling point: 318-332 ° C
-Density: 0.956 g/mL
Use:
- DMBAE is widely used in coatings and adhesives as a plasticizer.
-It can also be used as a reactive diluent, which can reduce the viscosity of the coating and chemically react with other compounds during the curing process.
Preparation Method:
- DMBAE is generally prepared by an acid-catalyzed alcohol amine reaction. First, dioleyl methanol and 4-(N,N-dimethylamino) butyric acid are mixed in a suitable solvent at a molar ratio of 1:1. Under the action of a catalyst, the reaction is heated, generate DMBAE.
Safety Information:
- DMBAE is a flammable liquid, away from fire and high temperature environment.
-Avoid direct contact with skin and eyes, and take personal protective measures, such as glasses, gloves and protective clothing, if necessary.
-Pay attention to ventilation during operation and avoid contact with strong oxidants.
-If inhalation or skin contact occurs, immediately stay away from the source, wash the affected area, and seek medical help.
-please read the product safety data sheet (SDS) before use.
Last Update:2024-04-10 22:29:15