O-CHLORO-L-PHENYLALANINE

O-CHLORO-L-PHENYLALANINE - Names and Identifiers

Name	2-Chloro-L-phenylalanine
Synonyms	L-2-Chlorophe H-Phe(2-Cl)-OH H-PHE(O-CL)-OH H-PHE(2-CL)-OH H-L-PHE(2-CL)-OH TIMTEC-BB SBB003552 H-O-CHLORO-L-PHE-OH RARECHEM BK PT 0001 L-2-Chlorophenylalanine 2-Chloro-L-phenylalanine O-CHLORO-L-PHENYLALANINE (2R)-2-ammonio-3-(2-chlorophenyl)propanoate (S)-2-AMINO-3-(2-CHLORO-PHENYL)-PROPIONIC ACID
CAS	185030-83-5 103616-89-3
InChI	InChI=1/C9H10ClNO2.ClH/c10-7-4-2-1-3-6(7)5-8(11)9(12)13;/h1-4,8H,5,11H2,(H,12,13);1H/t8-;/m0./s1

O-CHLORO-L-PHENYLALANINE - Physico-chemical Properties

Molecular Formula	C9H10ClNO2
Molar Mass	199.63
Melting Point	233-235°C
Boling Point	339.5°C at 760mmHg
Solubility	Insoluble in water
Appearance	White powder
Storage Condition	Sealed in dry,Room Temperature
MDL	MFCD00077921
Physical and Chemical Properties	Storage Conditions:? 20℃ WGK Germany:3

O-CHLORO-L-PHENYLALANINE - Risk and Safety

WGK Germany

O-CHLORO-L-PHENYLALANINE - Reference

Reference

1. Zhang, Chi, et al. "Components study on antitussive effect and holistic mechanism of Platycodonis Radix based on spectrum-effect relationship and metabonomics analysis." Journal of Chromatography B 1173 (2021): 122680.https://doi.org/10.1016/j.jchromb.2021
2. [IF=3.205] Chi Zhang et al."Components study on antitussive effect and holistic mechanism of Platycodonis Radix based on spectrum-effect relationship and metabonomics analysis."J Chromatogr B. 2021 May;1173:122680
3. [IF=3.205] Chi Zhang et al."Active microbial metabolites study on antitussive and expectorant effects and metabolic mechanisms of platycosides fraction of Platycodonis Radix."J Chromatogr B. 2022 Apr;1195:123171
4. [IF=4.411] Junfeng Hao et al."Comparative Analysis of Major Flavonoids among Parts of Lactuca indica during Different Growth Periods."Molecules. 2021 Jan;26(24):7445

O-CHLORO-L-PHENYLALANINE - Introduction

2-Chloro-L-phenylalanine is an organic compound that is a derivative of phenylalanine and contains a chlorine atom in its structure. The following is a description of the properties, uses, preparation and safety information of 2-choro-l-phenylalanine:

Nature:
-Appearance: 2-chroo-l-phenylalanine is white crystal or crystalline powder.
-Solubility: It is slightly soluble in water and soluble in acid and alkali.
-Melting point: The melting point of 2-Chloro-L-phenylalanine is about 200-220°C.

Use:
-Biochemical research: 2-chroo-l-phenylalanine is a commonly used chemical reagent, often used in the study of enzyme-catalyzed reactions, such as as reaction substrates or catalysts.
-Drug synthesis: 2-Chloro-L-phenylalanine plays an important role in drug synthesis and can be used as a synthetic precursor of certain drugs.

Method:
The preparation method of 2-Chloro-L-phenylalanine can be carried out by the following steps:
1. Phenylalanine is reacted with a chlorinating agent, such as thionyl chloride (SO2Cl2), to form a chlorinated derivative of 2-Chloro-L-phenylalanine.
2. Hydrolysis of chlorides under alkaline conditions to give 2-Chloro-L-phenylalanine.

Safety Information:
- 2-Chloro-L-phenylalanine is a chemical substance. When using, pay attention to safe operation and avoid direct contact with skin, eyes or inhalation of vapor.
-Pay attention to fire prevention and avoid contact with oxidants during use or storage.
-If ingested or inhaled, seek medical attention immediately.

Please note that the above information is for reference only. When using 2-choro-l-phenylalanine, be sure to refer to the relevant chemical laboratory procedures or professional advice.

Last Update：2024-04-09 15:17:54