O-TRIFLUOROMETHOXYBENZONITRILE

O-TRIFLUOROMETHOXYBENZONITRILE - Names and Identifiers

Name	2-(trifluoromethoxy)benzonitrile
Synonyms	o-Trifluoromethoxybenzonitrile o-Cyanotrifluoromethoxybenzene O-TRIFLUOROMETHOXYBENZONITRILE 2-Trifluorimethoxybenzonitrile 2-(TRIFLUOROMETHOXY)BENZONITRILE 2-(trifluoromethoxy)benzonitrile O-trifluoromethyl-methoxybenzonitrile 2,2,3,3,4,4,4-heptafluorobutyl trifluoromethanesulfonate 2-(TrifluoroMethoxy)benzonitrile(o-TrifluoroMethoxybenzonitrile)
CAS	63968-85-4
EINECS	264-584-0
InChI	InChI=1/C8H4F3NO/c9-8(10,11)13-7-4-2-1-3-6(7)5-12/h1-4H

O-TRIFLUOROMETHOXYBENZONITRILE - Physico-chemical Properties

Molecular Formula	C8H4F3NO
Molar Mass	187.12
Density	1,245 g/cm3
Boling Point	80 °C
Flash Point	80-82°C/15mm
Vapor Presure	0.305mmHg at 25°C
Appearance	Crystallization
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.449
MDL	MFCD00042409

O-TRIFLUOROMETHOXYBENZONITRILE - Risk and Safety

Risk Codes	R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S23 - Do not breathe vapour. S36/37 - Wear suitable protective clothing and gloves. S9 - Keep container in a well-ventilated place.
UN IDs	3276
HS Code	29269090
Hazard Note	Toxic
Hazard Class	6.1
Packing Group	III

O-TRIFLUOROMETHOXYBENZONITRILE - Introduction

2-(trifluoromethoxy)benzonitrile, chemical formula C8H4F3NO, is an organic compound. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: White crystalline solid
-Molecular weight: 183.12g/mol
-Solubility: Soluble in organic solvents, such as ethanol, dimethylformamide, etc.
-Melting point: 50-51°C
-Boiling point: 185-187°C (decomposition)

Use:
2-(trifluoromethoxy)benzonitrile can be used as organic synthesis intermediates, commonly used in drug synthesis, pesticide synthesis and synthesis of other organic compounds. It has potential anti-tumor activity in the pharmaceutical field and can be used to synthesize anti-tumor drugs. In addition, it can also be used as a raw material in the field of materials science for the preparation of polymer materials.

Preparation Method:
2-(trifluoromethoxy)benzonitrile can be obtained by the reaction of o-trifluoromethyl chlorobenzene and sodium cyanide. The specific steps are as follows: reacting o-trifluoromethyl chlorobenzene with sodium cyanide in an alcohol solvent to generate 2-(trifluoromethoxy)benzonitrile.

Safety Information:
2-(trifluoromethoxy)benzonitrile is an organic compound, and the following points should be paid attention to when using it:
-avoid contact with skin and eyes, such as contact should immediately rinse with plenty of water.
-Avoid inhaling its dust or vapor, and use it with appropriate ventilation equipment.
-Storage should be sealed and kept away from fire and oxidizing agents.
-Wear appropriate personal protective equipment such as goggles and gloves when using.

Last Update：2024-04-09 20:52:54