OH-PDLLA-OH

OH-PDLLA-OH - Names and Identifiers

Name	Poly(DL-lactide)OH
Synonyms	OH-PDLLA-OH Poly(DL-lactide)OH

OH-PDLLA-OH - Physico-chemical Properties

Appearance	Non-crystalline polymer, white-like to light yellowish brown irregular particles or powder
Storage Condition	-20℃
Sensitive	Easily absorbing moisture

OH-PDLLA-OH - Introduction

Poly(DL-lactide)OH(Poly(DL-lactide)OH) is a thermoplastic polymer with the following properties:

1. racemization: racemic polylactic acid is made by mixing and polymerizing D-lactic acid and L-lactic acid in equal amounts, so it has no specific optical activity.

2. hydroxyl end: the polymer has a hydroxyl end, which can participate in the reaction through the functional group to achieve further chemical modification.

3. biodegradability: racemic polylactic acid can be gradually hydrolyzed into lactic acid monomer in vivo, and finally metabolized by biological tissues and excreted in vitro.

Racemic polylactic acid has a wide range of applications, including medicine, biological materials and tissue engineering. Common applications include:

1. Drug sustained-release system: racemic polylactic acid can be used to prepare a carrier for sustained-release drugs, which has the characteristics of controlling the drug release rate and prolonging the drug action time.

2. tissue repair and regeneration: racemic polylactic acid can be used as a scaffold material in tissue engineering for repairing and regenerating tissues, such as bone tissue, cartilage tissue and nerve tissue.

3. slow release fertilizer: racemic polylactic acid can also be used as a slow release fertilizer raw materials, with the characteristics of controlled release of nutrients.

The common method for preparing Poly(DL-lactide)OH is to mix D-lactic acid and L-lactic acid through a polymerization reaction, and use a peroxide catalyst for the polymerization reaction. After completion of the polymerization, the terminal hydroxyl functional groups are obtained by appropriate treatment methods.

Regarding safety information, racemic polylactic acid is generally considered to be relatively safe and can be used for in vivo applications. However, during use and handling, care should be taken to avoid inhalation of dust and contact with skin, eyes, etc. At the same time, waste and residues need to be disposed of properly, and relevant safety procedures and use guidelines are followed.

Last Update：2024-04-09 21:11:58