OXANTEL
OXANTEL
CAS: 36531-26-7
Molecular Formula: C13H16N2O
OXANTEL - Names and Identifiers
OXANTEL - Physico-chemical Properties
| Molecular Formula | C13H16N2O |
| Molar Mass | 216.28 |
OXANTEL - References
| biological activity | Oxantel (CP-14445) is a derivative of Pyrantel (HY-12641), an agonist of the N-subtype AChR. Oxantel is an insect repellent with excellent insect repellent activity. |
| Target | nAChR |
| Cell Line: | T. muris |
| Concentration: | 0.015 µg/mL, 0.3 µg/mL, 0.6 µg/mL, 4.66 µg/mL, 9.375 µg/mL, 150 µg/mL, 600 µg/mL |
| Incubation Time: | 24 hours, 48 hours, 72 hours |
| Result: | Resulted in strongly reduced viabilities; resulted in strongly reduced viabilities within 24 hours but did not kill the worms. Inhibited T. muris in vivo. |
| Animal Model: | 4 week-old female C57BL/10 mice and 3 week-old male |
| Dosage: | 1 mg/kg, 2.5 mg/kg, 5 mg/kg, 10 mg/kg |
| Administration: | Intraperitoneal injection |
Last Update：2024-04-10 22:29:15
