Oxaprozin
Oxaprozin
CAS: 21256-18-8
Molecular Formula: C18H15NO3
Oxaprozin - Names and Identifiers
| Name | Oxaprozin |
| Synonyms | DAYPRO Oxapro Durapro OXAPROSIN Dxaprozin Oxaprozin OXAPROZINE Oxaprozinum Oxaprozin (200 mg) 4,5-DIPHENYL-2-OXAZOLEPROPANOIC ACID 2-Oxazolepropanoic acid, 4,5-diphenyl- 3-(4,5-DIPHENYL-2-OXAZOLYL)PROPIONIC ACID 4,5-Diphenyl-2-oxazolepropanoic acid, Daypro 3-(4,5-DIPHENYL-1,3-OXAZOL-2-YL)PROPIONIC ACID 3-(4,5-DIPHENYL-1,3-OXAZOL-2-YL)PROPANOIC ACID OXAPROZIN (3-(4,5-DIPHENYL-2-OXAZOLYL)PROPIONIC ACID) |
| CAS | 21256-18-8 |
| EINECS | 244-296-1 |
| InChI | InChI=1/C18H15NO3/c20-16(21)12-11-15-19-17(13-7-3-1-4-8-13)18(22-15)14-9-5-2-6-10-14/h1-10H,11-12H2,(H,20,21) |
| InChIKey | OFPXSFXSNFPTHF-UHFFFAOYSA-N |
Oxaprozin - Physico-chemical Properties
| Molecular Formula | C18H15NO3 |
| Molar Mass | 293.32 |
| Density | 1.2278 (rough estimate) |
| Melting Point | 154 °C |
| Boling Point | 435.17°C (rough estimate) |
| Flash Point | 236.2°C |
| Water Solubility | 4mg/L(37 ºC) |
| Solubility | Soluble in DMSO |
| Vapor Presure | 1.6E-09mmHg at 25°C |
| Appearance | Solid |
| Color | Crystals from methanol |
| Merck | 14,6924 |
| pKa | 4.3(at 25℃) |
| Storage Condition | 2-8°C |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
| Refractive Index | 1.5100 (estimate) |
| Use | Determination of content by UV method |
| In vitro study | Oxaprozin is a non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. Oxaprozin is used to treat rheumatoid arthritis, osteoarthritis, dysmenorrhea, and to relieve moderate pain. The anti-inflammatory effect of Oxaprozin is thought to be due to its inhibition of cyclooxygenase in platelets that blocks prostaglandin synthesis. The antipyretic effect may be due to an effect on the hypothalamus, leading to an increase in peripheral blood flow, vasodilation, and subsequent heat dissipation. Oxaprozin exhibits lower COX-2 selectivity, implying higher selectivity for COX-1. |
Oxaprozin - Risk and Safety
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S36 - Wear suitable protective clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
| RTECS | RP6990000 |
| HS Code | 29349990 |
| Hazard Note | Irritant |
| Toxicity | TDLo orl-rbt: 39 mg/kg (female 6-18D post):TER IYKEDH 15,250,84 |
Supplier List
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Multiple SpecificationsSpot supply
Product Name: Oxaprozin Visit Supplier Webpage Request for quotationCAS: 21256-18-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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