PD150606
PD 150606
CAS: 179528-45-1
Molecular Formula: C9H7IO2S
PD150606 - Names and Identifiers
PD150606 - Physico-chemical Properties
| Molecular Formula | C9H7IO2S |
| Molar Mass | 306.12 |
| Solubility | DMSO: >20mg/mL |
| Appearance | powder |
| Color | yellowish |
| Storage Condition | -20°C |
| Stability | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months. |
| In vitro study | PD150606 interacts with both calcium-binding domains (μ- and m-calpains) of Calpain. PD150606 attenuates hypoxic/hypoglycemic injury to cerebrocortical neurons in culture and excitotoxic injury to Purkinje cells in cerebellar slices. PD 150606 (25 μM; 0-12 hours) reduces Cycloheximide (10 mg/ml) -triggered apoptosis of neutrophils. |
PD150606 - Risk and Safety
| Hazard Symbols | T - Toxic |
| Risk Codes | R25 - Toxic if swallowed R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes R43 - May cause sensitization by skin contact |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 2811 6.1 / PGIII |
PD150606 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 3.267 ml | 16.333 ml | 32.667 ml |
| 5 mM | 0.653 ml | 3.267 ml | 6.533 ml |
| 10 mM | 0.327 ml | 1.633 ml | 3.267 ml |
| 5 mM | 0.065 ml | 0.327 ml | 0.653 ml |
Last Update：2024-01-02 23:10:35
PD150606 - Reference Information
| biological activity | PD 150606 is a selective, cell-permeable, non-peptide calpain inhibitor, the Ki for the effects of β-calpains and m-calpains were 0.21 μm and 0.37 μm, respectively, and showed neuroprotective activity. |
| Target | Ki: 0.21 μm (δ-calpains), 0.37 μm (m-calpains) |
Last Update：2024-04-09 20:52:54
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CAS: 179528-45-1
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Product Name: PD 150606 Visit Supplier Webpage Request for quotation
CAS: 179528-45-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 179528-45-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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