Molecular Formula | C18H15NO3
|
Molar Mass | 293.32 |
Density | 1.318±0.06 g/cm3(Predicted) |
Boling Point | 569.0±45.0 °C(Predicted) |
Solubility | DMSO :150 mg/mL (511.39 mM) |
pKa | 4.72±0.37(Predicted) |
Storage Condition | -20℃ |
Physical and Chemical Properties | Bioactivity PEO-IAA (2-(1H-Indol-3-yl)-4-oxo-4-phenyl-butyric acid) is a novel potent auxin antagonist that can bind to transport inhibitor response 1/auxin signaling F-box proteins (TIR1/AFBs). PEO-IAA not only inhibited the expression of auxin responsive ZmSAUR2 gene, but also inhibited the bending to gravity. |
Target | Target Value auxin () TIR1/AFBs |
In vitro study | PEO-IAA is also an α-alkyl-IAA, and shows more potent anti-auxin activity in auxin-responsive gene expression and in the cell division and elongation pathway that is mediated via SCF TIR1/AFBs . PEO-IAA suppresses not only the expression of an auxin-responsive ZmSAUR2 gene, but also gravitropic curvature. PEO-IAA blocks the auxin response in Arabidopsis, rice, moss and maize. |