PF 06650833 - Names and Identifiers
PF 06650833 - Physico-chemical Properties
Molecular Formula | C18H20FN3O4
|
Molar Mass | 361.37 |
Density | 1.34±0.1 g/cm3(Predicted) |
Boling Point | 621.0±55.0 °C(Predicted) |
Solubility | DMSO: ≥ 33 mg/mL |
Appearance | powder |
Color | white to beige |
pKa | 13.44±0.70(Predicted) |
Storage Condition | room temp |
PF 06650833 - Preparation solution concentration reference
| 1mg | 5mg | 10mg |
---|
1 mM | 2.767 ml | 13.836 ml | 27.673 ml |
5 mM | 0.553 ml | 2.767 ml | 5.535 ml |
10 mM | 0.277 ml | 1.384 ml | 2.767 ml |
5 mM | 0.055 ml | 0.277 ml | 0.553 ml |
Last Update:2024-01-02 23:10:35
PF 06650833 - Reference Information
biological activity | PF-06650833 is an effective IRAK4 selective inhibitor with IC50 of 0.2 nM. |
target | TargetValue IRAK4 (Cell-free assay) 0.2 nM |
Target | Value |
IRAK4
(Cell-free assay)
| 0.2 nM |
Last Update:2024-04-09 21:31:57