PF-06928215
PF-06928215
CAS: 2378173-15-8
Molecular Formula: C20H20N4O4
PF-06928215 - Names and Identifiers
PF-06928215 - Physico-chemical Properties
| Molecular Formula | C20H20N4O4 |
| Molar Mass | 380.4 |
| Appearance | Solid |
| Storage Condition | 2-8°C，密封，干燥 |
| In vitro study | PF-06928215 displays no activity in cellular cGAS assays measuring dsDNA-induced IFN-beta expression. |
PF-06928215 - Reference Information
| biological activity | PF-06928215 is a high affinity cGAS (cyclic GMP-AMP Synthase) inhibitor with IC50 of 4.9 μM and affinity Kd value of 0.2 μM. |
| target | IC50: 4.9 μM (cGAS) Kd: 0.2 μM |
| in vitro study | PF-06928215 displays no activity in cellular cGAS assays measuring dsDNA-induced IFN-beta expression. |
Last Update：2024-04-09 20:48:19
