Molecular Formula | C41H78NO8P |
Molar Mass | 744.033681 |
Density | approximate 1.47g/ml(20℃) |
Solubility | chloroform: 50mg/mL, slightly hazy, brown-yellow |
Appearance | solution |
Storage Condition | -20°C |
Hazard Symbols | Xn - Harmful |
Risk Codes | R22 - Harmful if swallowed R38 - Irritating to the skin R40 - Limited evidence of a carcinogenic effect R48/20/22 - R67 - Vapors may cause drowsiness and dizziness R36/38 - Irritating to eyes and skin. R20 - Harmful by inhalation R63 - Possible risk of harm to the unborn child R68/20/21/22 - R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R20/22 - Harmful by inhalation and if swallowed. |
Safety Description | S36/37 - Wear suitable protective clothing and gloves. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
UN IDs | UN 1888 6.1/PG 3 |
WGK Germany | 3 |
FLUKA BRAND F CODES | 1-8-10 |
HS Code | 2923202000 |
Reference Show more | 1. [IF=7.46] Sai Wang et al."Construction of a high affinity aptamer and an aptasensor with chitosan oligosaccharide-AuNPs@Fe2+ nanozyme for highly sensitive detection of phosphatidylserine."Sensor Actuat B-Chem. 2022 Jul;362:131800 |
Use | Phosphatidylethanolamine is also called cephalin. The natural phosphatidylethanolamine is extracted and refined from animal brain tissue or spinal cord with solvent; The synthesized phosphatidylethanolamine is obtained by the reaction of glycerol monophosphate difatty acid ester and ethanolamine. Phosphatidylethanolamine is mainly used as emulsifier and liposome carrier material in pharmaceutical agents, and is used to make emulsions and liposomes. In addition, it also has an antioxidant effect, but because it is expensive, it is rarely used as an antioxidant. |
Biosynthesis of phosphatidylethanolamine | Currently. It is not fully understood what substances regulate didiacyl day 1 oil to produce phosphatidylgeronine, phosphatidylethanolamine or triacylglycerol. In liver cells, yeasts and some bacteria, it is found that there are a route for the conversion of phosphatidylethanolamine to phosphatidylcholine. In this route, which includes three consecutive reactions, methyl from S-adenosylmethionine (AdoMet) is transferred to phosphatidylethanolamine. The transfer process is carried out under the catalysis of phosphatidylethanolamine-N-methyl transferase located on the endoplasmic reticulum. Through the methylation of phosphatidylethanolamine, liver cells realize the mutual transformation of phosphatidylcholine and phosphatidylethanolamine, and indirectly produce choline. The remaining four main phospholipids in eukaryotic cells are synthesized by CDP diacylglycerol, and their reaction mode is similar to the synthesis reaction of phosphatidylcholine and phosphatidylethanolamine, such as phosphatidylserine It can be obtained by the reaction of CDP diacylglycerol and serine catalyzed by phosphatidylethanolamine, or obtained by the base exchange reaction with serine, phosphatidylinositol can be obtained by the reaction of CDP di: acylglycerol and L-inositol catalyzed by phosphatidylinositol synthetase. |