Name | 4-nitrophenyl-β-D-galactopyranoside |
Synonyms | PNPG PNP-BETA-D-GAL PNP BETA-D-GALACTOPYRANOSIDE P-NITROPHENYL BETA-D-GALACTOSIDE 4-Nitrophenyl-α-D-galactophranoside 4-nitrophenyl-β-D-galactopyranoside NITROPHENYL-B-D-GALACTOPYRANOSIDE, 4- 4-Nitrophenyl beta-D-galactopyranoside 4-Nitrophenyl-beta-D-galactopyranoside P-NITROPHENYL BETA-D-GALACTOPYRANOSIDE 4-Nitrophenyl-B-D-Galactopyranoside(PNPG) |
CAS | 3150-24-1 200422-18-0 |
EINECS | 221-584-5 |
InChI | InChI=1/C12H15NO8/c14-5-8-9(15)10(16)11(17)12(21-8)20-7-3-1-6(2-4-7)13(18)19/h1-4,8-12,14-17H,5H2/t8?,9-,10+,11?,12+/m0/s1 |
InChIKey | IFBHRQDFSNCLOZ-AUCPDYOHSA-N |
Molecular Formula | C12H15NO8 |
Molar Mass | 301.25 |
Density | 1.3709 (rough estimate) |
Melting Point | 178-182°C |
Boling Point | 442.39°C (rough estimate) |
Specific Rotation(α) | [α]D20 -79~-85° (c=2, H2O)(calculated on the dried basis) |
Flash Point | 305.9°C |
Water Solubility | Soluble in DMSO, Methanol, Water. |
Vapor Presure | 2.14E-14mmHg at 25°C |
Appearance | White or yellowish powder |
Color | White to Almost white |
BRN | 92213 |
pKa | 12.55±0.70(Predicted) |
Storage Condition | Inert atmosphere,Store in freezer, under -20°C |
Sensitive | Easily absorbing moisture |
Refractive Index | 1.5200 (estimate) |
MDL | MFCD00063256 |
Use | The substrate of β-galactosidase was determined. |
Hazard Symbols | Xi - Irritant |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S24/25 - Avoid contact with skin and eyes. S36 - Wear suitable protective clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
WGK Germany | 3 |
FLUKA BRAND F CODES | 3-10-21 |
HS Code | 29389090 |
Reference Show more | 1. He Xu, Li Jianchong, Li Tingting et al. Effect of low concentration urea on the activity and stability of β-glucosidase from rubber seeds [J]. Journal of Hainan University (Natural Science) 2018(3):248-254. 2. Zhao Zihua, Zhang Feiran, Han Yongxu, etc. Antioxidant activity of selenium-enriched Chrysanthemum morifolium extract and its effects on α-amylase and α-glucosidase activities [J]. Natural product research and development, 2018, v.30(07):11-16. 3. Zhang Shuqiong, Geng Chang'an, Chen Xinglong, etc. Studies on the chemical constituents of Cycas rubra [J]. Natural product research and development, 2019, 031(001):75-80. 4. Zhao, Huading, et al. "Identification of major alpha-glucosidase inhibitors in radiastagali and its human Microsoft metabolites using ultrafiltration HPLC-DAD-MSn." Journal of pharmaceutical and biomedical analysis 104 (2015): 31-37.https://doi.org/10.1016 5. Mei, X., Yang, M., Zhu, L., Zhou, Q., Li, X., Chen, Z., & Zou, C. (2020). Retinal levels of amyloid beta correlate with cerebral levels of amyloid beta in young APPswe/PS1dE9 transgenic mice before onset of Alzheimer's disease. Behavioural Neurology, 2020. 6. [IF=5.118] Shan-Shan Zhang et al."Two Novel Multi-Functional Peptides from Meat and Visceral Mass of Marine Snail Neptunea arthritica cumingii and Their Activities In Vitro and In Vivo."Mar Drugs. 2018 Dec;16(12):473 7. [IF=3.493] Jie Zhang et al."Exploring the catalytic mechanism of a novel β-glucosidase BGL0224 from Oenococcus oeni SD-2a: Kinetics, spectroscopic and molecular simulation."Enzyme Microb Tech. 2021 Aug;148:109814 8. [IF=5.64] Xingyu Zhai et al."Structure and Function Insight of the α-Glucosidase QsGH13 From Qipengyuania seohaensis sp. SW-135.."Front Microbiol. 2022 Mar;13:849585-849585 |
Use | Substrate for β-D-glucosidase Substrate for determination of β-galactosidase. |