PROPANE-1,3-DIOL-DI-4-TOSYLATE

PROPANE-1,3-DIOL-DI-4-TOSYLATE - Names and Identifiers

Name	1,3-Propanediol di-p-toluenesulfonate
Synonyms	1,3-BIS(TOSYLOXY)PROPANE 1,3-PROPANEDIOL-DI-4-TOSYLATE Propane-1,3-diol-di-p-tosylate TRIMETHYLENE GLYCOL DITOSYLATE PROPANE-1,3-DIOL-DI-4-TOSYLATE Propanedioldiptoluenesulfonate TRIMETHYLENE GLYCOL DI-P-TOSYLATE 1,3-BIS(P-TOLUENESULFONYLOXY)PROPANE 1,3-PROPANEDIOL DI-P-TOLUENESULFONATE 1,3-Propanediol di-p-toluenesulfonate TRIMETHYLENE GLYCOL BIS(P-TOLUENESULFONATE) propane-1,3-diyl bis(4-methylbenzenesulfonate)
CAS	5469-66-9
InChI	InChI=1/C17H20O6S2/c1-14-4-8-16(9-5-14)24(18,19)22-12-3-13-23-25(20,21)17-10-6-15(2)7-11-17/h4-11H,3,12-13H2,1-2H3

PROPANE-1,3-DIOL-DI-4-TOSYLATE - Physico-chemical Properties

Molecular Formula	C17H20O6S2
Molar Mass	384.47
Density	1.300±0.06 g/cm3(Predicted)
Melting Point	90-92°C(lit.)
Boling Point	563.1±38.0 °C(Predicted)
Flash Point	294.4°C
Vapor Presure	3.98E-12mmHg at 25°C
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.56
MDL	MFCD00013392

PROPANE-1,3-DIOL-DI-4-TOSYLATE - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R22 - Harmful if swallowed
Safety Description	S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S24/25 - Avoid contact with skin and eyes.
WGK Germany	3
HS Code	29309090

PROPANE-1,3-DIOL-DI-4-TOSYLATE - Introduction

1,3-Propanediol di-p-toluenesulfonate is an organic compound with the chemical formula C14H18O6S2. It is a white solid which is soluble in organic solvents such as methanol, ethanol and dimethylformamide.

This compound is widely used in organic synthesis. It can be used as an intermediate in the synthesis of ethynyl and sulfating reagents. It is also an effective alcohol protecting group and can be used for hydroxyl protection reactions in organic synthesis. In addition, it can also be used as a reaction solvent or as a component of the ionic liquid.

The method for preparing 1,3-Propanediol di-p-toluenesulfonate is usually obtained by reacting p-methanesulfonic acid and 1,3-propanediol under acid-catalyzed conditions. The reaction conditions are generally at elevated temperatures, such as 100-120°C, and generally longer reaction times.

In terms of safety, the compound is generally stable and safe under normal conditions of use. However, it can cause irritation and allergic reactions, so use appropriate precautions, such as wearing respirators, chemical protective clothing and chemical safety goggles. At the same time, contact with skin, eyes and respiratory tract should be avoided to prevent discomfort or injury. In case of ingestion or contact, immediate care and consultation with a doctor should be undertaken.

Last Update：2024-04-10 22:29:15