PROPARACAINE
PROPARACAINE
CAS: 298-50-0
Molecular Formula: C16H26N2O3
PROPARACAINE - Names and Identifiers
PROPARACAINE - Physico-chemical Properties
| Molecular Formula | C16H26N2O3 |
| Molar Mass | 294.39 |
| pKa | pKa 3.22(H2O) (Uncertain) |
PROPARACAINE - Observation of side effects of propargaine eye drops in LASIK
from VIP
Author:
Abstract:
0.5% promethamine hydrochloride is widely used in ophthalmic surgery because of its fast action time and good anesthetic effect, but it has great toxicity. Laser in situ keratomileusis (LASIK) is the world's most advanced technology for the treatment of myopia, and the mode of anesthesia is surface anesthesia, so whether the operation can be carried out smoothly and the speed of postoperative visual acuity recovery is related to the amount of preoperative surface anesthetic. In order to observe the anesthetic effect and side effects of 0.5% proparticaine hydrochloride in LASIK, 100 patients with myopia were observed in March, and the results are reported as follows.
Key words:
LASIK side effects observe eye drops intraoperative anesthetic effect myopia sensitive Technology advantages
DOI:
10.3969/j.issn.1009-6493.2005.02.048
cited:
year:
2005
Last Update：2024-01-02 23:10:35
PROPARACAINE - method for the separation of proparacaine hydrochloride Intermediate IV from other intermediates by high performance liquid chromatography
from Google Patents
publication/announcement date:
Jun 1, 2016
inventor:
Abstract:
The invention discloses a high performance liquid chromatography method for separating the intermediate IV of promethamine hydrochloride from other intermediates, comprising the following steps: Step 1, take the sample of proparocaine hydrochloride, dissolve the sample of proparocaine hydrochloride with organic solvent, and prepare the sample solution containing 0.5~1.0mg proparocaine hydrochloride per 1ml, set the mobile phase of the liquid chromatograph, the flow rate of the mobile phase is 0.6~1.2/min, the detection wavelength is 232±3nm, and the column oven of the column of the liquid chromatograph is 20 ℃ ~ 40 ℃, 5-20 μl of the sample solution in step 1 is injected into the liquid chromatograph set up in step 2 to complete the separation of the intermediate IV of promethamine hydrochloride from other intermediates. The present procedure a method of The HPLC proparacaine hydrochloride
Last Update：2023-08-16 22:09:08
PROPARACAINE - Clinical application of ophthalmic surface anesthetics proparocaine hydrochloride and lidocaine
from hownet
Author:
Song Jianhong , Jia Yumei , Wang Yuanfeng
Abstract:
at present, there are very few optional products for clinical Ophthalmic surface anesthetics in China. Due to the promotion of imported products focused on large hospitals in large cities, some small-scale city and county-level primary hospitals in China, it is difficult to obtain the desired product. Promethamine hydrochloride eye drops and lidocaine injection are both commonly used in ophthalmic surface anesthesia, promethamine hydrochloride eye drops clinical application performance is reliable, convenient and concise operation, lidocaine injection
Key words:
lidocaine proparkinin surface anesthetics surface anesthetic Clinical application eye drops ophthalmology subconjunctival injection hydrochloric acid injection
DOI:
CNKI:SUN:SXHZ.0.2009-S2-084
cited:
year:
2009
Last Update：2023-08-16 22:09:08
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