PROPOFOL-IMI

PROPOFOL-IMI - Names and Identifiers

Name	2-Isopropyl-6-propylphenol (Propofol Impurity O)
Synonyms	Brn 4383251 PROPOFOL-IMI Propofol Impurity O Propofol EP Impurity O 2-(1-Methylethyl)-6-propyl 2-Isopropyl-6-propylphenol Phenol, 2-isopropyl-6-propyl- 2-(1-Methylethyl)-6-propylphenol 2-Isopropyl-6-propylphenol (Propofol Impurity O)
CAS	74663-48-2

PROPOFOL-IMI - Physico-chemical Properties

Molecular Formula	C12H18O
Molar Mass	178.27
Density	0.951±0.06 g/cm3(Predicted)
Boling Point	49-51 °C(Press: 0.3 Torr)
Solubility	Chloroform, Methanol (Slightly)
Appearance	Oil
Color	Colourless to Light Yellow
pKa	11.00±0.10(Predicted)
Storage Condition	Inert atmosphere,Room Temperature

PROPOFOL-IMI - Upstream Downstream Industry

Raw Materials	Phenol, 2-(1-methylethyl)-6-(1-propen-1-yl)- 2-Allyl-6-isopropylphenol 1-isopropyl-2-(methoxymethoxy)benzene Allyl O-Cumenyl Ether 2-Isopropylphenol
Downstream Products	2-N-PROPYLPHENOL 4-Propylphenol

PROPOFOL-IMI - Introduction

2-Isopropyl-6-propylphenol (Propofol Impurity O), also known as Propofol O, is one of the impurities of Propofol. Its molecular formula is C12H18O and its molecular weight is 178.27g/mol.

Nature:
2-Isopropyl-6-propylphenol (Propofol Impurity O) is a colorless liquid with a special aroma. It has a density of about 0.92 g/mL and a boiling point of about 245-250°C. It is stable at normal temperature and pressure.

Use:
2-Isopropyl-6-propylphenol (Propofol Impurity O) is mainly used as an intermediate of chemical reagents and drugs. It is widely used in the field of medicine and plays an important role in anesthesia, analgesia and sedation.

Method:
2-Isopropyl-6-propylphenol (Propofol Impurity O) can be obtained as a by-product of the synthesis of Propofol. In the preparation of Propofol, when the phenoxybenzoate reacts with isopropyl chloride, a part of the resulting product will undergo a displacement reaction to form 2-Isopropyl-6-propylphenol (Propofol Impurity O).

Safety Information:
2-Isopropyl-6-propylphenol (Propofol Impurity O) has low toxicity, but it should be used with caution. It is an organic solvent and should avoid contact with skin and eyes. During the operation, appropriate personal protective measures should be taken, such as wearing gloves and protective glasses. In addition, it should be stored in a dark, cool and dry place, away from fire and oxidizing agents. It is important to note that 2-Isopropyl-6-propylphenol (Propofol Impurity O) is intended for laboratory or professional use only and is prohibited for medical or therapeutic use on humans or animals. Before use, carefully read and follow the requirements of relevant safety manuals and labels.

Last Update：2024-04-09 20:52:54