Name | Pafuramidine |
Synonyms | DB289 Pafuramidine PAFURAMIDINE Unii-H1vg379J2x 4,4'-(2,5-Furandiyl)bis[N-methoxybenzenecarboximidamide] BenzenecarboxiMidaMide,4,4'-(2,5-furandiyl)bis[N-Methoxy- |
CAS | 186953-56-0 |
Molecular Formula | C20H20N4O3 |
Molar Mass | 364.4 |
Density | 1.25 |
Melting Point | 192.5-193 ºC |
Boling Point | 457.7±55.0 °C(Predicted) |
Solubility | DMSO (Slightly), Methanol (Slightly, Heated) |
Appearance | Solid |
Color | Pale Yellow to Light Yellow |
pKa | 6.01±0.50(Predicted) |
Storage Condition | -20°C Freezer, Under inert atmosphere |
Physical and Chemical Properties | Bioactive pafuramide (DB289) is an orally biocompatible drug of furamidine with anti-Pneumocystis Pneumonia activity. |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 2.744 ml | 13.721 ml | 27.442 ml |
5 mM | 0.549 ml | 2.744 ml | 5.488 ml |
10 mM | 0.274 ml | 1.372 ml | 2.744 ml |
5 mM | 0.055 ml | 0.274 ml | 0.549 ml |
biological activity | Pafuramidine (DB289) is an oral biocompatible furamidine drug with anti-pneumocystis pneumonia activity. |