Molecular Formula | C57H110O6 |
Molar Mass | 891.48 |
Melting Point | 72-75°C |
Boling Point | 260 °C |
Solubility | Practically insoluble in water; soluble in hexane and in hot propan-2-ol . |
Physical and Chemical Properties | White crystalline powder, odorless, slightly sweet and bitter, easily soluble in water. |
WGK Germany | - |
EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
uses | tromethamine is widely used in the preparation of buffers in biochemical and molecular biology experiments. It is also an intermediate for the preparation of surfactants, vulcanization accelerators and some drugs. It is a non-sodium amino buffer base, which can react with water in body fluids to reduce it; it is suitable for metabolic acidemia and also suitable for respiratory acidemia. It is suitable for metabolic acidemia and acute respiratory acidemia. Patients with acidemia are ideal drugs. |
Preparation | Tromethamine can be prepared by the corresponding nitro compound reduction or catalytic hydrogenation method; it can also be produced by the interaction of nitromethane and 3mol of formaldehyde. Methyl nitromethane is reduced to trimethylaminomethane. |