Paz·Naclone

Paz·Naclone

Pazinaclone

CAS: 103255-66-9

Molecular Formula: C25H23ClN4O4

Paz·Naclone - Names and Identifiers

Name	Pazinaclone
Synonyms	DN-2327 Pazinaclone Paz·Naclone 2-(7-chloro-1,8-naphthyridin-2-yl)-3-[2-(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-2-oxoethyl]-3h-isoindol-1-one 2-(7-Chloro-1,8-naphthyridine-2-yl)-3-[2-oxo-2-(1,4-dioxa-8-azaspiro[4.5]decane-8-yl)ethyl]isoindoline-1-one 8-[[2-(7-Chloro-1,8-naphthyridin-2-y1)-2,3-dihydro-3-oxo-1H-isoindol-1-y1]acetyl]-1,4-dioxa-8-azaspiro[4.5]decane 8-[[[2-(7-Chloro-1,8-naphthyridin-2-yl)-2,3-dihydro-3-oxo-1H-isoindol]-1-yl]acetyl]-1,4-dioxa-8-azaspiro[4.5]decane 1H-Isoindol-1-one,2-(7-chloro-1,8-naphthyridin-2-yl)-3-[2-(1,4-dioxa-8-azaspiro[4.5]dec-8-yl)-2-oxoethyl]-2,3-dihydro-
CAS	103255-66-9

Paz·Naclone - Physico-chemical Properties

Molecular Formula	C25H23ClN4O4
Molar Mass	478.93
Density	1.48±0.1 g/cm3(Predicted)
Melting Point	238-239°
Boling Point	712.5±60.0 °C(Predicted)
pKa	1.62±0.30(Predicted)
Physical and Chemical Properties	Colorless crystals are obtained from dichloromethane-ethyl acetate with a melting point of 238~239 ℃.

Paz·Naclone - References

Use	Anti-Anxiety drug. Non-benzodiazepines with mixed effects of agonism and antagonism of benzodiazepine receptors. In particular, the activity of the (S)-enantiomer is preferred.
production method	reaction of compound (I) with phosphine (II), product (III) the compound (IV) is obtained by re-hydrolysis, and then (V) is amidated to obtain the product.

Last Update：2024-04-10 22:29:15

Paz·Naclone

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Paz·Naclone

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