Perillartine
perillartine
CAS: 30950-27-7
Molecular Formula: C10H15NO
Perillartine - Names and Identifiers
Perillartine - Physico-chemical Properties
| Molecular Formula | C10H15NO |
| Molar Mass | 165.23 |
| Density | 1.0203 (rough estimate) |
| Melting Point | 102°C |
| Boling Point | 293.09°C (rough estimate) |
| Flash Point | 158.3°C |
| Solubility | DMSO : ≥ 100 mg/mL (605.22 mM);H2O : < 0.1 mg/mL (insoluble) |
| Vapor Presure | 0.000845mmHg at 25°C |
| Appearance | White to off-white (Solid) |
| Color | Very sweet crystals |
| pKa | 11.45±0.28(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Refractive Index | 1.5200 (estimate) |
| MDL | MFCD00019421 |
| In vitro study | The responses of the monomeric Tas1r2 subunits of human, rhesus monkey, squirrel monkey and mouse to Perillartine are examined, respectively. The human, rhesus monkey and squirrel monkey Tas1r2 subunits can be activated by Perillartine, while mouse Tas1r2 can not. The insensitivity of human, rhesus monkey, squirrel monkey and mouse Tas1r2 subunits to cyclamate precludes the probable involvement of Tas1r3 subunit in the assay. Replacement of the mouse Tas1r2 with rhesus monkey Tas1r2 (rhTas1r2/mTas1r3) leads to a gain of response to Perillartine. The dose-response curve show the efficacy of responses of the Tas1r2 subunits among species: hTAS1R2>rhTas1r2>smTas1r2>mTas1r2. These results demonstrate that the monomeric Tas1r2 subunit can be activated by Perillartine in a species-dependent manner. |
Perillartine - Risk and Safety
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| Toxicity | LD50 orl-rat: 2500 mg/kg AFDOAQ 15,82,51 |
Perillartine - Reference Information
| NIST chemical information | Information provided by: webbook.nist.gov (external link) |
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| traits | white crystal |
| overview | perilla essence is also called perilla essence. it is white crystal at normal temperature with slight perilla aroma. it is a kind of cigarette sweetener with high sweetness (sweetness is 2000 times that of sucrose), low calorie, non-toxic and good cigarette taste improvement effect, especially for medium and low grade cigarettes, it has been widely used in some brand-name cigarettes in Europe, America and Japan. It is suitable for flavoring or feeding of roasted cigarettes and mixed cigarettes, and the reference dosage is 0.002%-0.01%(20ppm-100ppm). |
| cigarette taste improver | perilla can obviously reduce irritation, remove bitter, astringent, spicy and other miscellaneous gases in cigarettes, make smoke softer and more delicate, and have a pure and comfortable aftertaste, thus obviously improving the quality of smoke. the quality grade of cigarettes can be improved without changing the raw materials of tobacco leaves, it is also possible to use lower tobacco raw materials without changing the grade of cigarette products. Adding perilla to cigarettes, the cost of cigarettes does not increase much, but the selling price of cigarette products can increase with the improvement of cigarette product quality. So that the cigarette factory can obtain obvious economic benefits. |
| method of use | dissolve perilla scape and dilute it to a 1% solution with 95% ethanol or propylene glycol. According to the 0.2%-0.5% of cut tobacco, weigh 1% perilla scape solution, spray it evenly on the cut tobacco, and pack it after drying. According to the different quality of cut tobacco, several groups of control experiments should be done to obtain the best ratio for mass production. |
| biological activity | Perillartine is a sweetener that activates taste receptor type 1 member 2 (TAS1R2). |
Last Update：2024-04-09 21:54:55
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Product Name: Perillartine Request for quotation
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CAS: 30950-27-7
Tel: 0731-86393263
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