Pinoresinol
Pinoresinol
CAS: 487-36-5
Molecular Formula: C20H22O6
Pinoresinol - Names and Identifiers
| Name | Pinoresinol |
| Synonyms | Pinoresinol (+)-PINORESINOL (1β,5β)-2β,6β-Bis(3-methoxy-4-hydroxyphenyl)-3,7-dioxabicyclo[3.3.0]octane (3R,3aβ,6aβ)-3β,6β-Bis(3-methoxy-4-hydroxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan 4,4'-[[(3aα,6aα)-Tetrahydro-1H,3H-furo[3,4-c]furan]-1α,4α-diyl]bis(2-methoxyphenol) (-)-4,4'-[[(3aα,6aα)-Tetrahydro-1H,3H-furo[3,4-c]furan]-1α,4α-diyl]bis(2-methoxyphenol) (1S)-1β,4β-Bis(4-hydroxy-3-methoxyphenyl)-3aβ,4,6,6aβ-tetrahydro-1H,3H-furo[3,4-c]furan (3aS,6aS)-3a,4,6,6a-Tetrahydro-3β,6β-bis(4-hydroxy-3-methoxyphenyl)-1H,3H-furo[3,4-c]furan 2-Methoxy-4-[(1R)-4α-(3-methoxy-4-hydroxyphenyl)-3aα,4,6,6aα-tetrahydro-1H,3H-furo[3,4-c]furan-1α-yl]phenol |
| CAS | 487-36-5 |
Pinoresinol - Physico-chemical Properties
| Molecular Formula | C20H22O6 |
| Molar Mass | 358.39 |
| Density | 1.385 g/cm3 |
| Melting Point | 112 °C |
| Boling Point | 556.5±50.0 °C(Predicted) |
| Specific Rotation(α) | +84.4 (Me2CO) |
| Solubility | Soluble in methanol, ether, slightly soluble in water |
| Appearance | Solid |
| Color | white to tan |
| pKa | 9.54±0.35(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| In vitro study | Pinoresinol facilitated death-inducing signaling complex formation to trigger a caspase-8-dependent apoptotic cascade activation in TRAIL-resistant glioblastoma cells. |
Pinoresinol - Risk and Safety
| WGK Germany | 3 |
Pinoresinol - Reference
| Reference Show more | 1. He, Mingzhen, et al. "Application of characteristic ion filtering with ultra-high performance liquid chromatography quadrupole time of flight tandem mass spectrometry for rapid detection and identification of chemical profiling in Eucommia ulmoides Oliv." 2. Chen, Yazhen, et al. "Effect of roasting and in vitro digestion on phenolic profiles and antioxidant activity of water-soluble extracts from sesame." Food and Chemical Toxicology 139 (2020): 111239.https://doi.org/10.1016/j.fct.2020.111239 3. [IF=6.023] Yazhen Chen et al."Effect of roasting and in vitro digestion on phenolic profiles and antioxidant activity of water-soluble extracts from sesame."Food Chem Toxicol. 2020 May;139:111239 4. [IF=3.205] Jia Jia et al."Screening of anti-complement active ingredients from Eucommia ulmoides Oliv. branches and their metabolism in vivo based on UHPLC-Q-TOF/MS/MS."J Chromatogr B. 2019 Aug;1124:26 |
Pinoresinol - Reference Information
| Introduction | pinoresin is a trace element, which mainly exists in the natural resin of plant pine. |
| Application | people use modern technology to purify the resin, after processing can be obtained light yellow powder material, can be used for drug production, can also be used for industrial processing. |
| biological activity | Pinoresinol is a plant-derived lignin used for defense in Trichinella spp. Pinoresinol greatly sensitizes cancer cells to TNF-related apoptosis-inducing ligand TRAIL-induced apoptosis. |
Last Update：2024-04-09 21:54:55
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