Molecular Formula | C22H20O8 |
Molar Mass | 412.39 |
Density | 1.365±0.06 g/cm3 (20 ºC 760 Torr) |
Melting Point | 191.73℃ |
Boling Point | 602.3±55.0 °C(Predicted) |
Solubility | Soluble in methanol, ethanol, DMSO and other organic solvents |
Appearance | Powder |
Storage Condition | 2-8℃ |
MDL | MFCD10566628 |
Physical and Chemical Properties | White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, comes from Taoerqi Sinopodophyllum hexandrum (Royle) Ying (Anhui has the highest content); The rhizome of octagonal lotus Dysosma versipellis (Hance) M. Cheng ex Ying (Anhui has the highest content). |
In vitro study | Podophyllotoxone inhibits human prostate cancer cells PC3 and DU145 growth with IC 50 values of 14.7 and 20.6 µM. |
biological activity | Podophyllotoxone was isolated from the root of dysosma. Podophyllotoxone inhibits tubulin tubulin polymerization. |
Target | microtumule/Tubulin |
Use | podophyllotoxin has antiviral and anti-inflammatory activity. |