Pomalidomide Impurity F

Pomalidomide Impurity F - Names and Identifiers

Name	5-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
Synonyms	Pomalidomide Impurity F Pomalidomide Impurity 25 Thalidomide 5-Aminoisoindoline Impurity 5-amino-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione 5-amino-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione 5-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione 5-Amino-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione 1H-Isoindole-1,3(2H)-dione, 5-amino-2-(2,6-dioxo-3-piperidinyl)-
CAS	191732-76-0

Pomalidomide Impurity F - Physico-chemical Properties

Molecular Formula	C13H11N3O4
Molar Mass	273.24414
Density	1.570±0.06 g/cm3(Predicted)
Melting Point	>300 °C
Boling Point	603.8±50.0 °C(Predicted)
Solubility	Aqueous Base (Slightly), DMSO (Slightly, Sonicated)
Appearance	Solid
Color	Green to Dark Green
pKa	10.83±0.40(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Room temperature

Pomalidomide Impurity F - Introduction

5-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione(5-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione) is an organic compound. The following is a description of its nature, use, formulation and safety information:

Nature:
5-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione is a white crystalline or crystalline powder. It is insoluble in water at room temperature and slightly soluble in common organic solvents such as ethanol and dimethyl sulfoxide. Its chemical formula is C13H11N3O4 and its molecular weight is 281.25.

Use:
5-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione is mainly used as a drug intermediate and plays an important role in the pharmaceutical industry. It can be used to synthesize a variety of drugs, such as anti-cancer drugs and anti-inflammatory drugs.

Method:
5-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1, the preparation method of 3-dione can be achieved through multi-step chemical reactions. Specifically, the target product can be synthesized from a starting material having an appropriate structure through a series of reaction steps.

Safety Information:
Relatively limited information is available on the safety and toxicity of 5-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione. However, when handling and using the substance, appropriate safety measures should be taken, such as wearing protective gloves and glasses, ensuring good ventilation conditions, and avoiding inhalation or skin contact. When using the substance, the relevant safety procedures and guidelines should be followed. For detailed safety information, reference should be made to the Material Safety Data Sheet (MSDS) provided by the supplier.

Last Update：2024-04-09 21:54:55

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