Pro-xylane

Pro-xylane - Names and Identifiers

Name	Hydroxypropyl tetrahydropyranitol
Synonyms	Pro-xylane Puri-Xylane Tetrahydropyrantriol Retinol Pro+Pro-xylane Pro-Xylane,Puri-Xylane Hydroxypropyl tetrahydropyranitol HYDROXYPROPYL TETRAHYDROPYRANTRIOL Nano Liposomal HYDROXYPROPYL TETRAHYDROPYRANTRIOL Nano liposomal hydroxypripyl tetrahydropyrantriol (2S,3R,4S,5R)-2-(2-hydroxypropyl)oxane-3,4,5-triol
CAS	439685-79-7
EINECS	213-767-3

Pro-xylane - Physico-chemical Properties

Molecular Formula	C8H16O5
Molar Mass	192.21
Density	1.368±0.06 g/cm3(Predicted)
Boling Point	376.0±42.0 °C(Predicted)
Appearance	Liquid
Storage Condition	2-8℃
Use	It is a kind of xylose derivative with anti-aging Active, which can promote the synthesis of collagen, make the skin stronger and more elastic, improve the fine lines of the neck, prevent aging

Pro-xylane - Nature

boiling point	376.0±42.0 °C(Predicted)
density	1.368±0.06 g/cm3(Predicted)
acidity coefficient (pKa)	13.55±0.70(Predicted)

Last Update：2024-04-10 22:29:15

Pro-xylane - Use

biological activity

Bose is produced by xylose conversion and has a wide range of biological activities. It can activate the synthesis of mucopolysaccharides (GAGs) and promote the production of hyaluronic acid and collagen; Bose can also improve the adhesion between the dermis and the epidermis. Degree, by inducing the synthesis of structural components of the dermis and epidermis, promote the regeneration of damaged tissues, help maintain the elasticity of the dermis, and. Studies have shown that Bose is easy to biodegrade, does not accumulate in organisms, and has no toxicity.

function

1. Stimulate the generation and construction of GAGs (dry polysaccharide extracellular matrix) (such as gel-like egg autoplasmic network and sugar as scaffolds and intercellular shock absorbers) to make the matrix gel-like, increasing the firmness of cells and skin.

2. As a channel to guide the passage of repair molecules, like some proteins that allow cells to grow.

3. Use the activity of extracellular matrix to send information to young cells and re-stimulate aging cells.

4. Strengthen basement membrane function and reduce allergy and inflammation.

The skin improvement effect of Bose is comprehensive, not only limited to the extracellular matrix, but also the connection between the matrix and cells, the density and firmness of the skin, and the promotion of type VI and Iv collagen egg self-production. Bose, together with nicotinamide and coagulation acid, is listed as Mr. Cai's three favorite multi-effect skin beautifying ingredients.

principle of action

Bose can stimulate the production of mucopolysaccharide GAGs and increase the water content between extracellular matrix. So as to fully fill the ECM gap, make the skin reduce wrinkles, appear more delicate. At the same time, it plays a role in DEJ, promoting the synthesis of collagen VII and collagen IV, making our epidermis and dermis more closely linked, making the whole skin plump, firmer and more elastic.

efficacy

Bose can induce the biosynthesis of GAGs mucopolysaccharide and PG proteoglycan in superficial cortex. The lack of GAGs and PG will lead to the decrease of skin water content and defense ability. Effectively promote the tight connection between epidermis and dermis is better fixed, and the skin is stronger and more flexible. Long-term use can effectively improve wrinkles and fine lines on the face and neck and promote the regeneration of damaged tissues.

Last Update：2024-04-10 22:29:15

Pro-xylane - Uses and synthesis methods

main efficacy

1. Activate mucopolysaccharides (GAGs) synthesis:

This high-tech ingredient, based on bionics principles, is synthesized by a sugar called xylose that activates mucopolysaccharides (GAGs).

There are a lot of mucopolysaccharides between the extracellular matrix (ECM) of our skin, most of which are carbohydrate polymers (GAG) composed of uronic acid and ammonia sugar, and these mucopolysaccharides play a very important role in the skin, because mucopolysaccharides can absorb moisture and play a role in preventing skin moisture loss.

At the same time, because mucopolysaccharide absorbs a lot of water, it can form a structure that can be imagined as a colloid composed of water. At the same time, the water absorption capacity of the molecular structure of these protein mucopolysaccharides GAGs makes the matrix network structure more elastic, thus helping to improve the firmness of cells and enhance the elasticity of skin. These are important factors that affect the elasticity and texture of skin.

2. Stimulate skin glucosamine (GAGs) production:

Hydroxypropyl tetrahydropyranyl is a glycoprotein mixture that can stimulate the production of skin aminoglycans (GAGs).

GAGs are the main components of the extracellular matrix, and the hyaluronic acid contained in it is one of the main components of GAGs. Hyaluronic acid has strong water absorption and storage capacity, and can be injected into the dermis layer to achieve the effect of filling and tender skin, and the skin is full and elastic. Hyaluronic acid is also commonly used to fill the sunken parts of the skin, including wrinkles.

from the skin structure, GAGS, skin dermis mainly collagen, elastin, extracellular matrix (including GAGs).

synthesis method

The original synthetic route of Bose is: a large amount of xylose (Xylose) extracted from beech is used as the main raw material, and acetylacetone (Acetylacetone) undergoes a Knoevenagel condensation reaction in an alkaline aqueous solution (I. e. active methylene compounds (such as malonate, β-keto, cyanoacetate, nitroacetate, etc.) under the catalysis of ammonia, amine or its carboxylate, it reacts with aldehydes and ketones to undergo aldehyde-alcohol condensation and dehydration to obtain α,β-unsaturated compounds) to generate 1-C-(beta-D-xylopyranosyl)-acetone. After that, it undergoes a reduction reaction with sodium borohydride to reduce the ketone carbonyl group in the product to obtain 1-C-(beta-D-xyranosyl)-2-hydroxy-propane, which is Bose (Pro-xylane).

Last Update：2024-04-09 21:54:55

Pro-xylane - Use

P> Puri-Xylane, commonly known as Bose, is a xylose derivative with anti-aging activity, which can promote the synthesis of collagen, make skin stronger and more elastic, improve neck fine lines and prevent aging. Bose is a mixture of glycoproteins derived from xylose. Because xylose is abundant in beech trees and has the ability to promote the production of glucosaminoglycans, namely mucopolysaccharides (GAGs). As Bose extracted from beech trees, its effect is similar to xylose.

Bose is also a non-ionic surfactant with good dispersion and emulsification properties. Therefore, the initial low concentration Bose has also been used as an emulsifier or dispersant for skin care products. But after all, there is a skin barrier barrier, and Bose itself has a weak biological activity. Therefore, Bose needs to reach a higher concentration on the skin surface before it can increase the absorption through penetration with the help of concentration gradient. However, the high-concentration Bose has a high viscosity and is not very comfortable to use, so the proportion of Bose in most products is not high.

Last Update：2024-04-09 01:59:49

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