Profenofos
Profenofos
CAS: 41198-08-7
Molecular Formula: C11H15BrClO3PS
Profenofos - Names and Identifiers
| Name | Profenofos |
| Synonyms | Polycron cga15324 CGA 15324S Profenofos Polycron E.C. Profenofos E.C. O-Ethyl S-propyl O-(2-chloro-4-bromophenyl)thiophosphate S-n-Propyl-O-ethyl-O-2-chloro-4-bromo phenyl thiophosphate O-Ethyl-S-n-propyl-O-(2-chloro-4-bromophenyl)thiophosphate O-4-bromo-2-chlorophenyl O-ethyl S-propyl phosphorothioate O-(4-bromo-2-chlorophenyl) O-ethyl S-propyl phosphorothioate 4-Bromo-2-chloro-1-(ethoxy-propylsulfanylphosphoryl)oxybenzene O-(4-bromo-2-chlorophenyl) O-ethyl S-propyl phosphorothioate profenofos (ISO) |
| CAS | 41198-08-7 |
| EINECS | 255-255-2 |
| InChI | InChI=1/C11H15BrClO3PS/c1-3-7-18-17(14,15-4-2)16-11-6-5-9(12)8-10(11)13/h5-6,8H,3-4,7H2,1-2H3 |
Profenofos - Physico-chemical Properties
| Molecular Formula | C11H15BrClO3PS |
| Molar Mass | 373.63 |
| Density | d20 1.455 |
| Melting Point | <25 °C |
| Boling Point | 110°C (0.001 torr) |
| Flash Point | 124℃ |
| Water Solubility | 28 mg l-1 (25 °C) |
| Vapor Presure | 1.24×10-4 Pa (25 °C) |
| Appearance | Oily Liquid |
| Specific Gravity | 1.455 (20℃) |
| Merck | 13,7860 |
| BRN | 2150258 |
| Storage Condition | APPROX 4°C |
| Refractive Index | n20D 1.5466 |
| MDL | MFCD00078736 |
| Physical and Chemical Properties | Boiling point 110°C (0.001 torr) |
| Use | For the control of cotton, vegetables, fruit trees and other crops of a variety of pests, especially the control of resistant cotton bollworm excellent |
Profenofos - Risk and Safety
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R24 - Toxic in contact with skin R20/22 - Harmful by inhalation and if swallowed. R43 - May cause sensitization by skin contact |
| Safety Description | S36/37 - Wear suitable protective clothing and gloves. S60 - This material and its container must be disposed of as hazardous waste. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S9 - Keep container in a well-ventilated place. S7 - Keep container tightly closed. |
| UN IDs | 3018 |
| WGK Germany | 3 |
| RTECS | TE6975000 |
| HS Code | 29309090 |
| Hazard Class | 6.1(b) |
| Packing Group | III |
| Toxicity | LD50 in rat (mg/kg): 358-400 orally; ~3300 dermally; LC50 (4 hr) in rat (mg/m3): ~3000 by inhalation (Buholzer); LC50 (96 hr) in rainbow fish: 0.91 mg/l (Kumar, Chapman). |
Profenofos - Upstream Downstream Industry
Profenofos - Reference Information
| LogP | 4.2 at 25℃ |
| NIST chemical information | Information provided by: webbook.nist.gov (external link) |
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| organophosphorus insecticide | profenofos is an organophosphorus insecticide with broad spectrum, high efficiency, medium toxicity and low residue, which was introduced into the market in the early 1980 s. Belongs to cholinesterase inhibitors. The individual optical isomers, due to the chiral phosphorus atom, show different insecticidal activity and acetylcholinesterase inhibition ability. Non-systemic insecticide and acaricide with touch and stomach toxicity, conduction and egg killing activity. Mainly used in cotton, corn, sugar beets, soybeans, potatoes, vegetables, tobacco and other crops, to control pests (especially lepidopteran pests) and mites. May cause cotton to turn slightly red. Probromophos is an ultra-efficient organophosphorus insecticide with contact and stomach toxicity effects, which is specially used to kill thorn-suction mouthpiece pests. The "National Food Safety Standard Maximum Residue Limits of Pesticides in Foods" (GB 2763-2016) stipulates that the maximum residue limit of profenofos in citrus is 0.2 mg/kg. A small amount of pesticide residues will not cause acute poisoning, but long-term consumption of food with excessive pesticide residues has a certain impact on human health. |
| characteristics of profenofos | 1. the effect of controlling resistant insects and mites is good. profenofos has a rapid effect and is still effective for other pests resistant to organophosphorus and pyrethroids. it is an effective agent for controlling resistant pests. 2. Compound and synergistic can be mixed with pyrethroids to give greater play to the efficacy of profenofos. It has a good effect on most agricultural pests, sucking and leaf-eating pests. 3. It has strong permeability and directly penetrates into the leaves and insects, and can kill the pests lurking in the leaves (back), paddy fields, fruits and burrowing into the straw. |
| control object | profenofos is an excellent representative variety of asymmetric organophosphorus insecticides, which is suitable for control of various mites, aphids, leaf miner, and noctuid, such as cotton bollworm, cotton aphid, red bollworm, Chilo suppressalis, rice leaf roller, leek maggots, etc. |
| usage | (1) mite control, 60-100 ml of 44% emulsifiable concentrate per mu and 60-100kg of water spray. (2) For aphid control, 30-60 ml of 44% emulsifiable concentrate and 30-60kg of water are sprayed per mu. (3) For the control of cotton bollworm, 60-100 ml of 44% emulsifiable concentrate and 60-100kg of water are sprayed per mu. (4) For the prevention and control of leek maggots, 300-500 ml of 50% emulsifiable concentrate and 450-800kg of water are sprayed per mu. |
| safety interval | profenofos is a moderately toxic insecticide. No chronic toxicity, no carcinogenic, teratogenic, mutagenic effect, no skin irritation, toxic to fish, birds, bees. Some data show that the safety interval required for different citrus crops is generally relatively long (21~100 days). The application of profenofos in citrus is strictly controlled in many places. |
| toxicity | acute oral LD50 of male rats is 358mg/kg, female is 316mg/kg, and acute percutaneous LD50 of rats is about 3300mg/kg(1008mg/kg). Accumulation toxicity test shows that the accumulation coefficient is greater than 5, which is mild accumulation. Ames test showed no mutagenic effect, and bone marrow cell micronucleus test showed no obvious effect on micronucleus rate and no teratogenic effect. Highly toxic to birds and fish. |
| use | asymmetric organophosphorus insecticide. It has contact and stomach toxicity, no systemic effect, wide insecticidal spectrum, and can prevent and control harmful insects and mites in cotton and vegetable fields. The dosage is: 2.5~5.0g active ingredient/100 m2 for pricking pests and mites; 6.7~12g active ingredient/100 m2 for chewing insects. It is used to control various pests of cotton, vegetables, fruit trees and other crops, especially the control effect of resistant cotton bollworm It is a systemic broad-spectrum insecticide, which can control harmful insects and mites in cotton and vegetable fields It is a ternary asymmetric non-systemic broad-spectrum insecticide, which has the effects of touch killing and stomach toxicity, and can control cotton, vegetables, fruit trees and other pests and mites. The application dose is based on the effective ingredients, 16-32g/mu for pricking insects and mites, 30-80g/mu for chewing insects, and has special effects for resistant cotton bollworm, and the use amount is 30-50g/mu preparation. |
| production method | preparation method-in the presence of acid binding agent, O-ethyl-S-propyl thiophosphoryl chloride is condensed with 2-chloro-4-bromophenol. O-ethyl-S-propyl thiophosphoryl chloride can be prepared from (C2H5O)2PCl, C2H5OPCl2, PCl3. The second preparation method uses ethanol as the solvent, O,O-diethyl-O-(2-chloro-4-bromophenyl) phosphate reacts with potassium thiohydride to form an intermediate compound, and then reacts with bromopropane to produce Probromophos. |
| category | pesticide |
| toxicity classification | highly toxic |
| acute toxicity | oral-rat LD50: 400 mg/kg; Oral-mouse LD50: 298 mg/kg |
| flammability hazard characteristics | Thermal decomposition discharges toxic sulfur oxides, phosphorus oxides, bromide and chloride fumes |
| storage and transportation characteristics | warehouse ventilation and low temperature drying; separate from food raw materials |
| fire extinguishing agent | water, dry powder, carbon dioxide, sand, foam |
| toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |
Last Update：2024-04-09 15:16:50
Supplier List
Multiple Specifications
Product Name: Profenofos Visit Supplier Webpage Request for quotationCAS: 41198-08-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Multiple Specifications
Product Name: Profenofos Visit Supplier Webpage Request for quotationCAS: 41198-08-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History
Raw Materials for Profenofos