Propargyl-PEG5-Tos
3,6,9,12-Tetraoxapentadec-14-yn-1-yl 4-methylbenzenesulfonate
CAS: 875770-32-4
Molecular Formula: C18H26O7S
Propargyl-PEG5-Tos - Names and Identifiers
Propargyl-PEG5-Tos - Physico-chemical Properties
| Molecular Formula | C18H26O7S |
| Molar Mass | 386.46 |
| Density | 1.177±0.06 g/cm3(Predicted) |
| Boling Point | 498.1±45.0 °C(Predicted) |
| Storage Condition | 2-8°C，存于惰性气体中 |
| MDL | MFCD28950765 |
| In vitro study | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
Propargyl-PEG5-Tos - Reference Information
| biological activity | Propargyl-PEG4-Tos is a PROTAC linker belonging to the PEG class. Propargyl-PEG4-Tos can be used to synthesize a range of PROTAC molecules. Propargyl-PEG4-Tos is a cleavable ADC linker for the synthesis of antibody-conjugated drugs (ADCs). |
Last Update：2024-04-09 21:32:11
