Name | Propynamide |
Synonyms | Propynamide Propiolamide HCequivCCONH2 2-Propynamide prop-2-ynamide PROPYNOIC ACID AMIDE Propiolic acid amide propynoic acid amide PropynoicAcidAmide,Propynamide |
CAS | 7341-96-0 |
InChI | InChI=1/C3H3NO/c1-2-3(4)5/h1H,(H2,4,5) |
InChIKey | HCJTYESURSHXNB-UHFFFAOYSA-N |
Molecular Formula | C3H3NO |
Molar Mass | 69.06 |
Density | 1.102±0.06 g/cm3(Predicted) |
Melting Point | 57-62 °C |
Boling Point | 134.6±23.0 °C(Predicted) |
Flash Point | 35.2°C |
Solubility | DMSO, Methanol |
Vapor Presure | 8.03mmHg at 25°C |
Appearance | Solid |
Color | Waxy Yellow |
pKa | 13.48±0.50(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 1.465 |
Hazard Symbols | Xn - Harmful |
Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. R36 - Irritating to the eyes |
Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
WGK Germany | 3 |
Application | propynolphthalamide is an important organic synthesis reagent, there are many applications in the synthesis of some natural products and their intermediates. |
preparation | 9. Add 8 grams of propiolic acid and phenol into 10 ml three bottles, add 50ml of anhydrous ethanol, and then add 20 grams of acetic acid according to, under stirring heated to 50 ℃, reaction 24 hours, after the reaction, after distilling off the ethanol, it was extracted 5 times with ether, each time 40ml, and the extract was distilled out of ether, and then cooled and filtered to prepare. The product was dried and weighed to give 5.3g. Yield 77%. |