Prulifloxacine
Prulifloxacin
CAS: 123447-62-1;123447-63-2
Molecular Formula: C21H20FN3O6S
Prulifloxacine - Names and Identifiers
Prulifloxacine - Physico-chemical Properties
| Molecular Formula | C21H20FN3O6S |
| Molar Mass | 461.46 |
| Density | 1.62±0.1 g/cm3(Predicted) |
| Melting Point | 211-214°C |
| Boling Point | 633.2±65.0 °C(Predicted) |
| Flash Point | 376.2°C |
| Solubility | 1 M NaOH: soluble25ML, clear, colorless (Solvent: 1 mg + 25 mL of NaOH) |
| Vapor Presure | 1.77E-20mmHg at 25°C |
| Appearance | White to yellow crystalline solid. |
| Color | Off-White to Pale Yellow |
| Maximum wavelength(λmax) | ['276nm(H2O)(lit.)'] |
| Merck | 14,7908 |
| pKa | 5.85±0.40(Predicted) |
| Storage Condition | Sealed in dry,Store in freezer, under -20°C |
| Refractive Index | 1.698 |
| Use | For the total synthesis of the class of antibacterial drugs |
| In vivo study | After oral administration of NM441 at a dose of 20 mg/kg to dogs, the peak concentration of NM394 in plasma was 2.39 micrograms/ml, whereas it was 0.63 micrograms/ml for NM394 administered alone. NM441 was as effective as ofloxacin and was twice as effective as ciprofloxacin against systemic infection with Staphylococcus aureus. Against infections with streptococci, NM441 was two to three times as effective as ofloxacin and five times as effective as ciprofloxacin. |
Prulifloxacine - Risk and Safety
| RTECS | XJ0600000 |
Prulifloxacine - Reference
| Reference Show more | 1. [IF=6.057] Song Hu et al."Reliable performance of aggregation-induced emission nanoparticle-based lateral flow assay for norfloxacin detection in nine types of animal-derived food."Talanta. 2020 Nov;219:121245 |
Prulifloxacine - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.167 ml | 10.835 ml | 21.67 ml |
| 5 mM | 0.433 ml | 2.167 ml | 4.334 ml |
| 10 mM | 0.217 ml | 1.084 ml | 2.167 ml |
| 5 mM | 0.043 ml | 0.217 ml | 0.433 ml |
Last Update：2024-01-02 23:10:35
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