Quinoline-8-carboxaldehyde - Names and Identifiers
Quinoline-8-carboxaldehyde - Physico-chemical Properties
Molecular Formula | C10H7NO
|
Molar Mass | 157.17 |
Density | 1.223±0.06 g/cm3(Predicted) |
Melting Point | 95-96°C |
Boling Point | 314.3±15.0 °C(Predicted) |
Flash Point | 151.9°C |
Water Solubility | Insoluble in water. |
Vapor Presure | 0.00047mmHg at 25°C |
Appearance | Yellow liquid |
Color | Light orange to Yellow to Green |
BRN | 113039 |
pKa | 3.45±0.17(Predicted) |
Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
Sensitive | Air Sensitive |
Refractive Index | 1.687 |
MDL | MFCD00805837 |
Quinoline-8-carboxaldehyde - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin.
R36/38 - Irritating to eyes and skin.
R43 - May cause sensitization by skin contact
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S37/39 - Wear suitable gloves and eye/face protection
S36/37 - Wear suitable protective clothing and gloves.
|
HS Code | 29334900 |
Hazard Class | IRRITANT |
Quinoline-8-carboxaldehyde - Introduction
Quinoline-8-carboxaldehyde, also known as quinoline-8-aldehyde, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
Quinoline-8-carboxaldehyde is a yellow to orange liquid with a special odor. It has low solubility and is soluble in ethanol and ether solvents. Its molecular formula is C10H7CHO and its molecular weight is 159.17g/mol.
Use:
Quinoline-8-carboxaldehyde can be used to synthesize other organic compounds, such as fluorescent dyes, drugs and coordination compounds. It can be used as an important intermediate in organic synthesis for the synthesis of quinoline compounds and derivatives.
Preparation Method:
Quinoline-8-carboxaldehyde can be synthesized by a variety of methods, the commonly used method is through the reduction reaction of hydroxybenzyl anisole with sodium nitrate and iron powder. The specific steps include mixing p-hydroxybenzyl anisole with sodium nitrate, sulfuric acid and nitric acid, heating to the end of the reaction, cooling, filtering and concentrating the reaction mixture. The product obtained is decarboxylated by heating to give a Quinoline-8-carboxaldehyde.
Safety Information:
Quinoline-8-carboxaldehyde irritating and toxic, need to pay attention to safe operation. In case of contact with skin, eyes or respiratory tract, rinse immediately with plenty of water and seek medical help. During use or storage, it is necessary to avoid contact with oxidants and acidic substances to prevent dangerous reactions.
Last Update:2024-04-09 19:05:49