RA375 - Names and Identifiers
RA375 - Physico-chemical Properties
| Molecular Formula | C30H25ClN4O7
|
| Molar Mass | 589.00 |
| Solubility | DMSO:60mg/mL |
| Storage Condition | -20℃ |
| Use | RA375 is an inhibitor of RPN13 (26S proteasome subunit). RA375 activates UPR signaling, ROS production, and apoptosis. The anti-tumor activity of RA375 is 10 times that of RA190. |
RA375 - Reference
| Reference Show more | 1. Ravi K Anchoori, et al. Structure-function Analyses of Candidate Small Molecule RPN13 Inhibitors With Antitumor Properties. PLoS One. 2020 Jan 15;15(1):e0227727. |
RA375 - Preparation solution concentration reference
| | 1mg | 5mg | 10mg |
|---|
| 1 mM | 1.698 ml | 8.489 ml | 16.978 ml |
| 5 mM | 0.34 ml | 1.698 ml | 3.396 ml |
| 10 mM | 0.17 ml | 0.849 ml | 1.698 ml |
| 5 mM | 0.034 ml | 0.17 ml | 0.34 ml |
Last Update：2024-01-02 23:10:35
