Name | CPI-1189 |
Synonyms | REN1189 CPI-1189 REN 1189 CPI 1189 CPI1189(REN-1189) REN-1189(CPI-1189) 4-Acetamido-N-(tert-butyl)benzamide Benzamide, 4-(acetylamino)-N-(1,1-dimethylethyl)- |
CAS | 183619-38-7 |
Molecular Formula | C13H18N2O2 |
Molar Mass | 234.29 |
Density | 1.102±0.06 g/cm3(Predicted) |
Melting Point | 119-121 °C |
Boling Point | 458.3±28.0 °C(Predicted) |
Solubility | DMSO:23.4mg/mL |
pKa | 14.65±0.70(Predicted) |
Storage Condition | -20°C |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 4.268 ml | 21.341 ml | 42.682 ml |
5 mM | 0.854 ml | 4.268 ml | 8.536 ml |
10 mM | 0.427 ml | 2.134 ml | 4.268 ml |
5 mM | 0.085 ml | 0.427 ml | 0.854 ml |
biological activity | CPI-1189 (REN 1654, REN 1189) is an inhibitor of tumor necrosis factor (TNF) alpha. CPI-1189 in the cells can inhibit the activation of p38 mitogen activated protein kinase phosphorylation, and play a neuroprotective role. |
Target | Value |