Risperidone
risperidone
CAS: 106266-06-2
Molecular Formula: C23H27FN4O2
Risperidone - Names and Identifiers
Risperidone - Physico-chemical Properties
| Molecular Formula | C23H27FN4O2 |
| Molar Mass | 410.48 |
| Density | 1.38±0.1 g/cm3(Predicted) |
| Melting Point | 170°C |
| Boling Point | 572.4±60.0 °C(Predicted) |
| Flash Point | 9℃ |
| Water Solubility | 44.74mg/L(25 ºC) |
| Solubility | Soluble in DMSO (10 mM), ethanol (10 mM), chloroform, and methanol. Insoluble in water. |
| Vapor Presure | 4.14E-13mmHg at 25°C |
| Appearance | White to white-like powder |
| Color | white to off-white |
| Merck | 14,8233 |
| pKa | pKa 8.3 (Uncertain) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.676 |
| MDL | MFCD00274576 |
| Physical and Chemical Properties | Crystallized from dimethylformamide-isopropanol, melting point 170.0 °c. Acute toxicity LD50 male and female mice, male and female rats, male and female dogs (mg/kg):29.7,26.9,34.3,35.4,14.1,18.3 intravenous injection; 82.1,63.1,113,56.6,18.3,18.3 Po. |
| Use | Antipsychotics |
Risperidone - Risk and Safety
| Risk Codes | R25 - Toxic if swallowed R39/23/24/25 - R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. R11 - Highly Flammable |
| Safety Description | S28 - After contact with skin, wash immediately with plenty of soap-suds. S36 - Wear suitable protective clothing. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37 - Wear suitable protective clothing and gloves. S16 - Keep away from sources of ignition. |
| UN IDs | 3249 |
| WGK Germany | 3 |
| RTECS | UV1164800 |
| HS Code | 29333990 |
| Hazard Class | 6.1(a) |
| Packing Group | II |
| Toxicity | LD50 in male, female mice, rats, dogs (mg/kg): 29.7, 26.9, 34.3, 35.4, 14.1, 18.3 i.v.; 82.1, 63.1, 113, 56.6, 18.3, 18.3 orally (Janssen, 1988) |
Risperidone - Reference
| Reference Show more | 1. [IF=6.057] Wen-Hua Ji et al."A water-compatible magnetic molecularly imprinted polymer for the selective extraction of risperidone and 9-hydroxyrisperidone from human urine."Talanta. 2018 May;181:392 2. [IF=3.119] Jinrui Zhang et al."In silico study on identification of novel MALT1 allosteric inhibitors."Rsc Adv. 2019 Nov;9(67):39338-39347 |
Risperidone - Introduction
Risperidone is an atypical sedative used in the treatment of schizophrenia.
Last Update：2022-10-16 17:11:48
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