S(+)-N,N-DIMETHYL-3-HYDROXY-3-(2-THIENYL)-1-PROPANAMINE - Names and Identifiers
S(+)-N,N-DIMETHYL-3-HYDROXY-3-(2-THIENYL)-1-PROPANAMINE - Physico-chemical Properties
Molecular Formula | C9H15NOS
|
Molar Mass | 185.29 |
Density | 1.111±0.06 g/cm3(Predicted) |
Melting Point | 74-76°C |
Boling Point | 290.1±30.0 °C(Predicted) |
Solubility | Chloroform (Slightly), Methanol (Slightly) |
Appearance | Solid |
Color | White to Off-White |
pKa | 14.35±0.20(Predicted) |
Storage Condition | Room Temperature, under inert atmosphere |
S(+)-N,N-DIMETHYL-3-HYDROXY-3-(2-THIENYL)-1-PROPANAMINE - Introduction
(S)-N, N-dimethyl-3-hydroxy-3-(2-thienyl) propylamine is an organic synthetic compound often abbreviated as 2-HTPA. Its chemical structure contains functional groups of thiophene and amine groups. The following is a description of the nature, use, preparation and safety information of 2-HTPA:
Nature:
-Appearance: White or off-white crystalline solid
-Melting point: about 118-119°C
-Solubility: Soluble in organic solvents such as ethanol, chloroform and dichloromethane
Use:
- 2-HTPA is often used as a catalyst or intermediate in organic synthesis, especially plays an important role in the synthesis of chiral drugs.
-It can carry out effective catalytic reactions without having a severe impact on the environment and the human body.
- 2-HTPA is essential for the construction of chiral structures with enantioselectivity.
Preparation Method:
The preparation methods of 2-HTPA are various. The common method is through the condensation reaction of 2-thiophenecarboxamide and dimethyl bromoacetate, and reduction under the catalysis of alkali.
Safety Information:
- 2-HTPA does not have obvious toxicity and irritation to human body under general use conditions, but it still needs to comply with general chemical safety operation specifications.
-It should be kept away from fire and high temperature, stored in a dry, well-ventilated place.
-Wear appropriate personal protective equipment, such as lab gloves and safety glasses.
-If ingestion or contact with skin or eyes, rinse immediately with plenty of water and seek medical help.
Please follow the chemical practices and safety requirements issued by the relevant agencies according to your specific needs.
Last Update:2024-04-09 15:17:51