S-2-苄基琥珀酸
(S)-2-Benzylsuccinic acid
CAS: 3972-36-9
Molecular Formula: C11H12O4
S-2-苄基琥珀酸 - Names and Identifiers
| Name | (S)-2-Benzylsuccinic acid |
| Synonyms | Benzylsuccinicacid S-Benzyl succinic acid Mitiglinide intermediate (S)-2-BENZYLSUCCINIC ACID (S)-2-Benzylsuccinic acid Mitiglinide intermediate 8 Mitiglinide intermediate 2 (2S)-2-benzylbutanedioic acid (S)-2-BENZYL-1,4-BUTANEDIOIC ACID (S)-2-Benzylsuccinic acid (Mitiglinide) Butanedioicacid, 2-(phenylmethyl)-, (2S)- |
| CAS | 3972-36-9 |
| EINECS | 609-742-5 |
| InChI | InChI=1/C11H12O4/c12-10(13)7-9(11(14)15)6-8-4-2-1-3-5-8/h1-5,9H,6-7H2,(H,12,13)(H,14,15)/t9-/m0/s1 |
S-2-苄基琥珀酸 - Physico-chemical Properties
| Molecular Formula | C11H12O4 |
| Molar Mass | 208.21 |
| Density | 1.290±0.06 g/cm3(Predicted) |
| Melting Point | 164.0 to 168.0 °C |
| Boling Point | 331.4±22.0 °C(Predicted) |
| Flash Point | 168.4°C |
| Vapor Presure | 6.23E-05mmHg at 25°C |
| Appearance | White solid |
| Color | White to Almost white |
| pKa | 3.97±0.10(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.567 |
| MDL | MFCD00798341 |
S-2-苄基琥珀酸 - Risk and Safety
| HS Code | 29173990 |
S-2-苄基琥珀酸 - Reference Information
| introduction | (S)-2-benzylsuccinic acid has a melting point of 164 to 168 degrees, a boiling point of 331.4±22.0 (under one atmospheric pressure), a density of 1.3, and a white to off-white crystalline solid under normal temperature and pressure. This compound is a common chiral synthesis intermediate. |
| Synthesis method | For the synthesis of (S)-2-benzyl succinic acid, the conventional synthesis method is based on its olefin structure, through appropriate reduction Under the action of hydrogenation, the double bond is hydrogenated, and the chirality during hydrogenation can be controlled to obtain the desired product configuration, which is the same as other hydrogenation reactions, if the reaction effect is good, pure products can be obtained without post-processing. It is worth noting that the following figure shows the synthesis of (R)-2-benzyl succinic acid, but the product route for synthesizing the S configuration is the same, except that the configuration of the chiral ligand needs to be changed. |
| Use | (S)-2-benzylsuccinic acid is a common asymmetric synthetic intermediate. The carboxyl group in the structure can be converted into common Active functional groups, such as hydroxyl groups under the reduction of borane. In addition, the two carboxyl groups in the structure can be heated, dehydrated and condensed in the presence of acetic anhydride or acetyl chloride to obtain the corresponding anhydride structure. |
Last Update：2024-04-09 21:01:54
Supplier List
Product Name: Mivacurium Chloride Impurity 1 Monomer Request for quotation
CAS: 3972-36-9
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
CAS: 3972-36-9
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Product Name: (S)-2-Benzylsuccinic acid Request for quotation
CAS: 3972-36-9
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
CAS: 3972-36-9
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Multiple Specifications
Product Name: (S)-2-Benzylsuccinic Acid Visit Supplier Webpage Request for quotationCAS: 3972-36-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Product Name: Mivacurium Chloride Impurity 1 Monomer Request for quotation
CAS: 3972-36-9
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
CAS: 3972-36-9
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Product Name: (S)-2-Benzylsuccinic acid Request for quotation
CAS: 3972-36-9
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
CAS: 3972-36-9
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Multiple Specifications
Product Name: (S)-2-Benzylsuccinic Acid Visit Supplier Webpage Request for quotationCAS: 3972-36-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History