S-Adenosyl-DL-methionine
AdoMet
CAS: 17176-17-9
Molecular Formula: C15H22N6O5S
S-Adenosyl-DL-methionine - Names and Identifiers
| Name | AdoMet |
| Synonyms | SAM-E AdoMet ADEMETHIONINE S-adenosyl methionione S-ADENOSYL-L-METHIONINE S-Adenosyl-DL-methionine s-(5'-deoxyadenosine-5'-yl) s-(5'-deoxyadenosine-5'-yl)methionine s-(5'-adenosyl)-l-methionine p-toluenesulfonate salt |
| CAS | 17176-17-9 |
S-Adenosyl-DL-methionine - Physico-chemical Properties
| Molecular Formula | C15H22N6O5S |
| Molar Mass | 398.44 |
| Melting Point | 78℃ |
| Solubility | H2O: soluble100mg/mL |
| Storage Condition | Sealed in dry,Room Temperature |
| MDL | MFCD00063498 |
| Physical and Chemical Properties | Physical and chemical properties S-adenosine methionine (S-Adenosyl-Lmethionine,SAM) is the only injection drug in liver-protecting and choleretic drugs, that is, S-adenosine methionine for injection with butanedisulfonic acid, with remarkable curative effect and no side effects, which is favored by patients. At the same time, SAM also has a good therapeutic effect on depression and arthritis, and its market demand is huge. S-adenosine methionine is an important metabolite commonly found in all biological cells. It participates in the transmethylation reaction, transsulfur reaction and transaminopropyl reaction of cells, methylation modification of important molecules in the cell, sulfur group storage and transfer; and the synthesis of arginine and spermatine ammonia play an irreplaceable role. |
| Use | Use methyl donors; cofactors for enzyme-catalyzed methylation reactions, including catechol O-methyltransferase (COMT) and DNA methyltransferase (DNMT). Although present in all cells, 85% of all methylation reactions occur in the liver and also regulate liver function, growth and injury. |
S-Adenosyl-DL-methionine - Reference
| Reference Show more | 1. Ye Xin Sun Wenjia Wang Yuan Li successfully song Yanhua Plum gang soup Huifang. Effects of S-adenosylmethionine on uterine smooth muscle contraction [J]. Chinese Journal of Modern Applied Pharmacy, 2017, 34(06):806-810. 2. Liao, Xueli, et al. "Identification of key odorants responsible for cooked corn-like aroma of green teas made by tea cultivar 'Zhong Huang 1 ′." Food Research International 136 (2020): 109355.https://doi.org/10.1016/j.foodres.2020.109355 |
S-Adenosyl-DL-methionine - Biological activity
S-Adenosyl-DL-methionine is a derivative of Ademetionine (HY-B0617). Ademetionine is an intermediate metabolite of methionine.
Last Update：2024-04-10 22:29:15
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