S-Boc-2-mercapto-4,6-dimethylpyrimidine

S-Boc-2-mercapto-4,6-dimethylpyrimidine - Names and Identifiers

Name	tert-Butyl S-(4,6-dimethylpyrimidin-2-yl) thiolcarbonate
Synonyms	BOC-S BOC-SDP 2-BOC-THIO-4,6-DIMETHYLPYRIMIDINE Butyldimethylpyrimidinthiolcarbonate S-Boc-2-mercapto-4,6-dimethylpyrimidine T-BOC-S-2-MERCAPTO-4,6-DIMETHYLPYRIMIDINE BOC-S S-Boc-2-mercapto-4,6-dimethylpyrimidine 2-(TERT-BUTOXYCARBONYLTHIO)-4,6-DIMETHYLPYRIMIDINE tert-Butyl S-(4,6-dimethylpyrimidin-2-yl) thiolcarbonate tert-Butyl-5-(4,6-dimethylpyrimidine-2-yl)thiolcarbonate S-tert-Butyloxycarbonyl-2-mercapto-4,6-dimethylpyrimidin S-TERT-BUTYLOXYCARBONYL-2-MERCAPTO-4,6-DIMETHYLPYRIMIDINE S-(TERT-BUTOXYCARBONYL)-2-MERCAPTO-4,6-DIMETHYLPYRIMIDINE O-TERT-BUTYL-S-(4,6-DIMETHYLPYRIMIDIN-2-YL) THIOLCARBONATE O-tert-butyl S-(4,6-dimethylpyrimidin-2-yl) carbonothioate Boc-S~S-(tert-Butoxycarbonyl)-2-mercapto-4,6-dimethylpyrimidine~tert-Butyl S-(4,6-dimethylpyrimidin-2-yl)thiolcarbonate
CAS	41840-28-2
EINECS	255-562-1
InChI	InChI=1/C11H16N2O2S/c1-7-6-8(2)13-9(12-7)16-10(14)15-11(3,4)5/h6H,1-5H3
InChIKey	POTDIELOEHTPJN-UHFFFAOYSA-N

S-Boc-2-mercapto-4,6-dimethylpyrimidine - Physico-chemical Properties

Molecular Formula	C11H16N2O2S
Molar Mass	240.32
Density	1.15g/cm³
Melting Point	48-51 °C (lit.)
Boling Point	358.8°C at 760 mmHg
Flash Point	>230°F
Vapor Presure	2.48E-05mmHg at 25°C
BRN	396984
Storage Condition	2-8°C
Refractive Index	1.534
MDL	MFCD00006080

S-Boc-2-mercapto-4,6-dimethylpyrimidine - Risk and Safety

Safety Description	S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes.
WGK Germany	3
HS Code	29335990

S-Boc-2-mercapto-4,6-dimethylpyrimidine - Introduction

tert-Butyl S-(4, +) thiolcarbonate(tert-Butyl S-(4, +) thiolcarbonate) is a compound with the following properties:

1. Appearance: This compound is usually a white to light yellow solid, and sometimes it can be a light yellow to yellow oily liquid.
2. molecular formula: C11H17N3O2S
3. Molecular weight: 249.34g/mol
4. Solubility: It can be dissolved in most organic solvents, such as dimethyl sulfoxide (DMSO) and dichloromethane (DCM).
5. Melting point: Its melting point range is 75-80°C, but there is no definite melting point in the form of oily liquid.
The main use of tert-Butyl S-(4,) thiolcarbonate is as a protecting group (protecting group) in organic synthesis. It can protect the amine function from other reaction conditions, so that the chemical reaction of specific sites occurs. When desired, the protecting group can be removed by suitable reaction conditions.

This compound can be synthesized by the following methods:
First, 2 mercapto-4, 6-dimethylpyrimidine reacts with anhydrous di-tert-butyl carbonate to generate tert-Butyl S-(4, 5-dimethylpyrimidine) thiolcarbonate.
Chemical equation: 2-dimethylpyrimidine di-tert-butyl carbonate → tert-Butyl S-(4, 5-mercapto) thiolcarbonate di-tert-butanol.

Regarding safety information, this compound may be dangerous, so proper safe operating procedures should be followed when handling. It can be irritating and corrosive and contact with skin and eyes should be avoided. When using, should wear appropriate protective gloves and safety glasses. Also, this compound should be stored in a dry place protected from light and away from sources of fire and heat.

Last Update：2024-04-10 22:29:15