S-Cbz-L-Cysteine
H-Cys(Z)-OH
CAS: 1625-72-5
Molecular Formula: C11H13NO4S
S-Cbz-L-Cysteine - Names and Identifiers
| Name | H-Cys(Z)-OH |
| Synonyms | H-Cys(Z)-OH H-CYS(Z)-OH H-Cys(Cbz)-OH S-Z-L-CYSTEINE S-Cbz-L-Cysteine S-CBZ-L-CYSTEINE S-Cbz-L-cysteine l-cysteine(z)-oh Nε-Carbobenzyloxy-L-cysteine S-CBZ-L-CYSTEINE CRYSTALLINE N-BENZYLOXYCARBONYL-L-CYSTEINE S-[(benzyloxy)carbonyl]cysteine S-[(benzyloxy)carbonyl]-L-cysteine |
| CAS | 1625-72-5 |
| InChI | InChI=1/C11H13NO4S/c12-9(10(13)14)7-17-11(15)16-6-8-4-2-1-3-5-8/h1-5,9H,6-7,12H2,(H,13,14) |
S-Cbz-L-Cysteine - Physico-chemical Properties
| Molecular Formula | C11H13NO4S |
| Molar Mass | 255.29 |
| Density | 1.358±0.06 g/cm3(Predicted) |
| Boling Point | 435.6±55.0 °C(Predicted) |
| Flash Point | 217.2°C |
| Vapor Presure | 2.33E-08mmHg at 25°C |
| pKa | 1.93±0.10(Predicted) |
| Storage Condition | Sealed in dry,Store in freezer, under -20°C |
| Refractive Index | 1.602 |
S-Cbz-L-Cysteine - Risk and Safety
| WGK Germany | 3 |
S-Cbz-L-Cysteine - Introduction
H-Cys(Z)-OH is a derivative compound with some specific properties and uses. The following is a description of its nature, use, preparation and safety information:
Nature:
H-Cys(Z)-OH is a cysteine derivative with a protecting group. It is a white crystalline solid which is soluble in organic solvents such as methanol, acetone and dichloromethane at room temperature. It has a carbonyl group (Cbz) in its chemical structure that protects the amine group from unwanted reactions.
Use:
H-Cys(Z)-OH has a wide range of applications in chemical synthesis. It is often used as a protecting group for cysteine to prevent non-specific reactions from occurring at the amine group. By using H-Cys(Z)-OH, the selectivity of cysteine in the chemical reaction can be effectively controlled, thereby synthesizing the target compound. In addition, H-Cys(Z)-OH can also be used in peptide synthesis, drug development and organic chemistry.
Method:
The method for preparing H-Cys(Z)-OH is relatively complicated. A common synthesis method is to synthesize N-Cbz-L-cysteine first, and then to obtain H-Cys(Z)-OH by acylation reaction of N-Cbz-L-cysteine with Butyronitrile under alkaline conditions.
Safety Information:
H-Cys(Z)-OH is relatively safe under normal circumstances, but the following points still need to be paid attention. First of all, it should be stored in a dry, cool place, away from direct sunlight. Second, avoid inhaling dust during use and avoid contact with skin and eyes. In case of contact, rinse with plenty of water and seek medical help. Finally, follow appropriate laboratory safety practices and waste disposal requirements to ensure safe use.
Nature:
H-Cys(Z)-OH is a cysteine derivative with a protecting group. It is a white crystalline solid which is soluble in organic solvents such as methanol, acetone and dichloromethane at room temperature. It has a carbonyl group (Cbz) in its chemical structure that protects the amine group from unwanted reactions.
Use:
H-Cys(Z)-OH has a wide range of applications in chemical synthesis. It is often used as a protecting group for cysteine to prevent non-specific reactions from occurring at the amine group. By using H-Cys(Z)-OH, the selectivity of cysteine in the chemical reaction can be effectively controlled, thereby synthesizing the target compound. In addition, H-Cys(Z)-OH can also be used in peptide synthesis, drug development and organic chemistry.
Method:
The method for preparing H-Cys(Z)-OH is relatively complicated. A common synthesis method is to synthesize N-Cbz-L-cysteine first, and then to obtain H-Cys(Z)-OH by acylation reaction of N-Cbz-L-cysteine with Butyronitrile under alkaline conditions.
Safety Information:
H-Cys(Z)-OH is relatively safe under normal circumstances, but the following points still need to be paid attention. First of all, it should be stored in a dry, cool place, away from direct sunlight. Second, avoid inhaling dust during use and avoid contact with skin and eyes. In case of contact, rinse with plenty of water and seek medical help. Finally, follow appropriate laboratory safety practices and waste disposal requirements to ensure safe use.
Last Update：2024-04-09 21:01:54
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