S-Etodolac - Names and Identifiers
Name | (S)-(+)-Etodolac
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Synonyms | RAK 592 S-Etodolac (S)-(+)-Etodolac (+)-(S)-Etodolac (S)-(+)-Etodolic acid (1S)-1,8-Diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid Pyrano[3,4-b]indole-1-acetic acid, 1,8-diethyl-1,3,4,9-tetrahydro-, (S)- Pyrano[3,4-b]indole-1-acetic acid, 1,8-diethyl-1,3,4,9-tetrahydro-, (1S)-
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CAS | 87249-11-4
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S-Etodolac - Physico-chemical Properties
Molecular Formula | C17H21NO3
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Molar Mass | 287.35 |
Melting Point | >133°C (dec.) |
Solubility | Chloroform (Sparingly), DMSO (Slightly), Methanol (Slightly) |
Appearance | Solid |
Color | White to Off-White |
Storage Condition | -20°C Freezer |
S-Etodolac - Introduction
(S)-( )-Etodolac is a non-steroidal anti-inflammatory drug, belonging to the acetic acid class of non-steroidal anti-inflammatory drugs (NSAIDs), with analgesic, anti-inflammatory and antipyretic effects. Its chemical name is (S)-( )-2-(1,8-diethyl-4, 9-dihydroxy-4-nonynyl)-3-methylaminoic acid, chemical formula is C17H21NO3, molecular weight is 287.36g/mol.
(S)-( )-Etodolac is commonly used to treat arthritis, rheumatoid arthritis, gout, and other pain and inflammation-related conditions. It inhibits the cyclooxygenase in the body, thereby reducing the synthesis of inflammatory mediators prostaglandins, to relieve pain and reduce inflammation.
There are various methods for preparing (S)-( )-Etodolac, and the commonly used method is to obtain a higher purity product through Chiral synthesis. A common synthesis method is to start from 2,5-dimethoxybenzaldehyde and gradually synthesize the target compound by chemical reaction.
Regarding safety information, use caution when using (S)-( )-Etodolac. Some potential side effects include gastrointestinal discomfort, indigestion, headaches, etc. Serious side effects may include gastrointestinal bleeding, kidney damage, and allergic reactions. Consult your doctor before use and strictly follow the dosage and medication guidelines to reduce possible risks.
Last Update:2024-04-10 22:29:15