S-adenosylmethionine
S-adenosylmethionine
CAS: 485-80-3
Molecular Formula: C15H23N6O5S
S-adenosylmethionine - Names and Identifiers
| Name | S-adenosylmethionine |
| Synonyms | 13CH3-SAM Methionine,active S-adenosylmethionine S-ADENOSYLMETHIONINE S-(5'-Adenosyl)methionine MEFKEPWMEQBLKI-AIRLBKTGSA-O S-Adenosyl-L-methionine sulfate p-toluene sulfonate salt 5'-Adenosyl(methyl)(3-amino-4-oxo-4-hydroxybutyl)sulfonium 5'-[(3-Amino-3-carboxypropyl)methylsulfonio]-5'-deoxyadenosine |
| CAS | 485-80-3 |
S-adenosylmethionine - Physico-chemical Properties
| Molecular Formula | C15H23N6O5S |
| Molar Mass | 400.45 |
S-adenosylmethionine - S-adenosylmethionine in the treatment of depression
from VIP Journal Professional Edition
Author:
Abstract:
objective: to observe the antidepressant effect and adverse reactions of a new natural antidepressant, S-adenosyl adductor. Methods: 31 cases of various depressive disorders were treated with open drug. Hamilton depression scale and Clinical Global Impression were used to evaluate the clinical efficacy. Results: the effective rate of patients with all hot is 72.5%. The course analysis found that the drug had a faster onset of action, with a significant decline in the rating scale on the fourth day of treatment.
Key words:
depression drug therapy S-adenosylmethionine
DOI:
CNKI:SUN:ZXWS.0.1998-02-014
cited:
year:
1998
Last Update：2024-01-02 23:10:35
S-adenosylmethionine - Clinical research progress of S-adenosylmethionine
from VIP
Author:
Abstract:
The liver is a very important metabolic and detoxification organ, liver cells are vulnerable to chemical substances, accumulation of metabolites and viral infection, leading to liver cell damage, and then progress to cirrhosis, liver cancer. S. Adenosylmethionine (S-adenosyl-L-methionine,SAMe) is a natural substance that exists in various organisms, differentiation and regulation of liver cells play an important role in sensitivity to various injuries. In the past, it has played a role in the treatment of cholestatic liver disease and other fields. Recent studies have shown that as a methyl group donor, SAMe can inhibit the expression of oncogenes, reduce tumor invasiveness and slow down the distant metastasis of tumors by inducing gene hypermethylation and reversing the overall hypomethylation, it opens up the possible application prospect of SAMe in the field of tumor prevention and treatment.
Key words:
ademetionine cholestatic liver disease malignant tumor transmethyl effect
DOI:
CNKI:SUN:XXHB.0.2010-33-015
cited:
year:
2010
Last Update：2023-08-16 22:09:08
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