SAS-PEG-SAS - Names and Identifiers
SAS-PEG-SAS - Physico-chemical Properties
SAS-PEG-SAS - Introduction
SAS-PEG-SAS(SAS-PEG-SAS) is a polymer compound with the following properties:
-Structure: SAS-PEG-SAS is a polymer composed of two bissuccinamide (SAS) groups connected by a polyethylene glycol (PEG) chain. The length of the PEG chain can be adjusted as desired.
-Solubility: SAS-PEG-SAS can be dissolved in water, and has good solubility and stability.
-Biocompatibility: SAS-PEG-SAS show excellent biocompatibility in vivo, are non-toxic to cells and tissues, and can reduce the toxic and side effects of drugs.
SAS-PEG-SAS has a wide range of applications in the field of medicine and biomedicine:
-Drug delivery system: SAS-PEG-SAS is used as a carrier of the drug delivery system, which can wrap the drug in it and transport the drug to the target location through targeted or slow-release methods, improving the efficacy of the drug and reducing side effects.
-Improve drug stability: SAS-PEG-SAS can protect drugs from oxidation, light and degradation in the environment, and improve drug stability and storage time.
-Polymer materials: SAS-PEG-SAS can be used to prepare polymer materials, such as hydrogels, nanoparticles and polymer films, etc., and have a wide range of applications in tissue engineering and medical devices.
The method of preparing SAS-PEG-SAS is mainly through chemical synthesis:
1. First, bis-succinic acid amide is reacted with succinyl chloride to generate bis-succinic acid amide succinyl ester.
2. Then, the disuccinamide succinyl ester is reacted with the polyethylene glycol containing the active hydroxyl group, and the SAS-PEG-SAS is generated by esterification or condensation reaction.
When using the SAS-PEG-SAS, you need to pay attention to the following safety information:
-Because SAS-PEG-SAS has certain chemical activity, it is necessary to avoid direct contact with skin and eyes to prevent irritation or other uncomfortable reactions.
-In the preparation and operation process, should comply with laboratory safety practices, take appropriate protective measures, such as wearing gloves, goggles, etc.
-For waste and solutions in synthesis and application, they should be properly disposed of in accordance with local environmental regulations.
Last Update:2024-04-09 21:04:16