Name | Sulfabenzamide |
Synonyms | SB Sulfabenzamide SulfabenzaMide, USP Sulfabenzamide (200 mg) N1-Benzoylsulfanilamide Sulfabenzamide Solution, 100ppm N-[(4-Aminophenyl)sulfonyl]-benzamide Sulfabenzamide,N-(4-Aminobenzenesulfonyl)benzamide |
CAS | 127-71-9 |
EINECS | 204-859-4 |
InChI | InChI=1/C13H12N2O3S/c14-11-6-8-12(9-7-11)19(17,18)15-13(16)10-4-2-1-3-5-10/h1-9H,14H2,(H,15,16) |
Molecular Formula | C13H12N2O3S |
Molar Mass | 276.31 |
Density | 1.3261 (rough estimate) |
Melting Point | 180-184 °C |
Water Solubility | 0.3 g/L (20 ºC) |
Solubility | Soluble in DMSO. Water solubility (g/L,20°C):0.3 |
Appearance | White to off-white solid |
Color | White to almost white |
Merck | 14,8897 |
BRN | 2139003 |
pKa | 4.57(at 25℃) |
Storage Condition | Keep in dark place,Inert atmosphere,2-8°C |
Sensitive | Sensitive to heat |
Refractive Index | 1.6360 (estimate) |
MDL | MFCD00044890 |
Physical and Chemical Properties | melting point 180-184°C |
In vitro study | Treatment of T-47D cells with Sulfabenzamide inhibited their proliferation and increased Caspase-3 activity. Sulfabenzamide did not induce apoptosis in them, but rather caused a minimal transition of the cell cycle from G1 to S and G2/M phases. |
Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
UN IDs | 3249 |
WGK Germany | 3 |
RTECS | CV5802500 |
HS Code | 29350090 |
Hazard Class | 6.1(b) |
Packing Group | III |
EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
biological activity | Sulfabenzamide (Sultrin, N-Sulfanilylbenzamide) is an antibacterial agent, which can also exert anti-tumor effect through various ways. |
use | sulfamobenzoyl has inhibitory effect on staphylococcus, pseudomonas aeruginosa and proteus. the combined application with ST SA can greatly enhance the antibacterial effect. |