Molecular Formula | C18H28N2O3S |
Molar Mass | 352.49 |
Density | 1.188 |
Boling Point | 512.9±56.0 °C(Predicted) |
Solubility | 10 mM in DMSO |
Appearance | solid |
pKa | 8.88±0.10(Predicted) |
Storage Condition | Inert atmosphere,2-8°C |
WGK Germany | 3 |
biological activity | SB269970 is a 5-HT7 receptor antagonist with a pKi of 8.3 and greater than 50-fold selectivity for other receptors. |
Animal Model: | male C57BL6/J mice |
Dosage: | 3, 10, 30 mg/kg |
Administration: | Intraperitoneal injection; once |
Result: | Significantly blocked amphetamine and ketamine-induced hyperactivity. |