SC-202671

Name	JNK Inhibitor IX
Synonyms	SC-202671 TCS JNK 5a JNK Inhibitor IX N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)-1-naphthamide N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thien-2-yl)-1-naphthalenecarboxamide N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thienyl-2-yl)-1-naphthalenecarboxamide 1-NaphthalenecarboxaMide, N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thien-2-yl)- N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thien-2-yl)-1-naphthalenecarboxamide JNK Inhibitor IX
CAS	312917-14-9

Molecular Formula	C20H16N2OS
Molar Mass	332.42
Density	1.32±0.1 g/cm3 (20 ºC 760 Torr)
Melting Point	88-90oC
Boling Point	486.8±45.0 °C(Predicted)
Solubility	Soluble in DMSO (up to 13 mg/ml with warming) or in Ethanol (up to 4 mg/ml with warming)
Appearance	Tan solid
Color	Off-white
pKa	11.95±0.20(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Stability	Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
In vitro study	JNK inhibitor IX significantly reduces caspase-3 activity in human skin fibroblasts by inhibiting JNK activity JNK inhibitor IX-mediated inhibition of JNK by preventing complete dephosphorylation of c-ABL on serine residues, significantly increased apoptotic death after imatinib mesylate (IM) treatment.

Last Update：2024-01-02 23:10:35

biological activity	JNK inhibitor IX (TCS JNK 5a) is a highly selective inhibitor of JNK, its pIC50 for JNK2 and JNK3 were 6.5 and 6.7, respectively.
Target	Value
JNK3	6.7(pIC50)
JNK2	6.5(pIC50)

Last Update：2024-04-09 21:54:55

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CAS: 312917-14-9
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Spot supply

Product Name: JNK Inhibitor IX Visit Supplier Webpage Request for quotation
CAS: 312917-14-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409

Wechat: 18301782025

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SC-202671

SC-202671 Request for Quotation