SCHEMBL2302444

SCHEMBL2302444 - Names and Identifiers

Name	(4R,12aS)-N-(2,4-difluorobenzyl)-7-benzylhydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
Synonyms	SCHEMBL2302444 Dolutegravir Intermediate4 3 4 6-TRICHLOROBENZYL ALCOHOL 97 (4R,12aS)-N-[(2,4-Difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-4-methyl-6,8-dioxo-7-(phenylmethox (4R,12aS)-7-(benzyloxy)-N-(2,4-difluorobenzyl)-4-Methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-[1,3]oxazino[3,2-d]pyrido[1,2-a]pyrazine-9-carboxaMide
CAS	1206102-11-5

SCHEMBL2302444 - Physico-chemical Properties

Molecular Formula	C27H25F2N3O5
Molar Mass	509.5
Density	1.42±0.1 g/cm3(Predicted)
Boling Point	761.7±60.0 °C(Predicted)
pKa	10.67±0.40(Predicted)
Storage Condition	Sealed in dry,Room Temperature

SCHEMBL2302444 - Upstream Downstream Industry

Raw Materials

(S)-7-phenylMethoxy-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1,2,4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylic acid Methyl ester
4-benzyloxy-3-oxobutyric acid methyl ester
(4R,12aS)-7-(benzyloxy)-9-broMo-4-Methyl-3,4-dihydro-2H-[1,3]oxazino[3,2-d]pyrido[1,2-a]pyrazine-6,8(12H,12aH)-dione
Methyl 5-[[[(2,4-difluorophenyl)methyl]amino]carbonyl]-1-(2-oxoethyl)-4-oxo-3-[(phenylmethyl)oxy]-1,4-dihydro-2-pyridinecarboxylate
4H-Pyran-2-carboxaldehyde, 4-oxo-3-(phenylmethoxy)-
2,4-Difluorobenzylamine
Methyl 3-(benzyloxy)-1-(2,3-dihydroxypropyl)-4-oxo-1,4-dihydropyridine-2-carboxylate
DiMethyl 3-(benzyloxy)-1-(2,2-diMethoxyethyl)-4-oxo-1,4-dihydropyridine-2,5-dicarboxylate
(R)-3-AMINO-1-BUTANOL
diMethyl 3-(benzyloxy)-4-oxo-4H-pyran-2,5-
2-(2-hydroxy-2-phenylethyl)-3-[(phenylmethyl)oxy]-4H-pyran-4-one
Methyl 3-(benzyloxy)-5-((2,4-difluorobenzyl)carbamoyl)-1-(2,2-dimethoxyethyl)-4-oxo-1,4-dihydropyridine-2-carboxylate
3-(BENZYLOXY)-2-METHYL-4H-PYRAN-4-ONE
carbon monoxide
3-Hydroxy-2-methyl-4H-pyran-4-one

SCHEMBL2302444 - Introduction

(4R,12AS)-N-(2,4-difluorobenzyl) -7-phenoxy-4-methyl-6, 8-dioxo-3, 4,6,8,12,12A-hexahydro-9-carboxy-2H-pyrido [1 ',2':4,5] pyrazino [2,1-B][1,3]-Oxazine-9-carboxamide is an organic synthetic compound. The following is a description of its nature, use, preparation and safety information:

Nature:
This compound is a solid with a specific chemical structure. It has a molecular formula of C26H22F2N4O4 and a molecular weight of 498.48g/mol.

Use:
The compound has certain application value in the field of medicine. It may have anti-cancer or anti-viral activity and has the potential to be used in the research and development of new drugs.

Method:
preparation of (4R,12AS)-N-(2,4-difluorobenzyl)-7-phenoxy -4-methyl -6,8-dioxy -3,4,6,8,12,12A-hexahydro -9-carboxy -2H-pyrido [1 ',2':4,5] pyrazino [2,1-B][1, A particular method of 3]-oxazinane-9-carboxamide would involve a series of chemical synthesis steps, including reaction and purification processes. These steps may be based on specific research literature or patents.

Safety Information:
Information on the safety and toxicity of this compound may be limited. Since it is a new synthetic compound, the effects on humans and the environment may not be fully understood. Therefore, when conducting relevant experiments or applications, it is necessary to follow appropriate laboratory safety procedures, and conduct comprehensive evaluation and control of the experimental process.

Last Update：2024-04-09 21:54:55