SD-171-02 - Names and Identifiers
Name | METICRANE
|
Synonyms | Arresten SD 17102 METICRANE SD-171-02 thiochroman-7-sulfonamide,6-methyl-,1,1-dioxide 1,1-diketo-6-methyl-3,4-dihydro-2H-thiochromene-7-sulfonamide 3,4-DIHYDRO-6-METHYL-2H-1-BENZOTHIOPYRAN-7-SULFONAMIDE-1,1-DIOXIDE 6-METHYL-1-THIA-1,2,3,4-TETRA-HYDRONAPHTHALENE-7-SULFONAMIDE 1,1-DIOXIDE
|
CAS | 1084-65-7
|
EINECS | 214-112-4 |
SD-171-02 - Physico-chemical Properties
Molecular Formula | C10H13NO4S2
|
Molar Mass | 275.34 |
Density | 1.4366 (rough estimate) |
Melting Point | 236-237° |
Boling Point | 549.1±60.0 °C(Predicted) |
Appearance | neat |
pKa | 9.71±0.20(Predicted) |
Storage Condition | Sealed in dry,2-8°C |
Refractive Index | 1.6800 (estimate) |
In vivo study | Meticrane, a thiazide diuretic is highly ranked in the connectivity map (cMap) analysis, and it does not have any known anti-cancer or immune-stimulating effect. Co-treatment with Meticrane significantly enhances treatment efficacy of CTLA-4 blockade. |
SD-171-02 - Risk and Safety
WGK Germany | 2 |
RTECS | XK6360000 |
SD-171-02 - Preparation solution concentration reference
| 1mg | 5mg | 10mg |
---|
1 mM | 3.632 ml | 18.159 ml | 36.318 ml |
5 mM | 0.726 ml | 3.632 ml | 7.264 ml |
10 mM | 0.363 ml | 1.816 ml | 3.632 ml |
5 mM | 0.073 ml | 0.363 ml | 0.726 ml |
Last Update:2024-01-02 23:10:35
SD-171-02 - Reference Information
biological activity | Meticrane is a diuretic that can inhibit the reabsorption of reabsorption ofsodiumandchlorideions in distal curved tubules. Meticrane can be used to treat essential hypertension. |
target | Sodium and chloride ion |
in vivo research | Meticrane, a thiazide diuretic is highly rank in the connectivity map (cMap) analysis, and it does not have any known anti-cancer or stimulating effect. Co-treatment with Meticrane significantly enhances treatment efficacy of CTLA-4 blockade. |
EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
Last Update:2024-04-10 22:29:15