SIA
Iodoacetic acid n-hydroxysuccinimide ester
CAS: 39028-27-8
Molecular Formula: C6H6INO4
SIA - Names and Identifiers
SIA - Physico-chemical Properties
| Molecular Formula | C6H6INO4 |
| Molar Mass | 283.02 |
| Density | 2.11±0.1 g/cm3(Predicted) |
| Melting Point | 148°C |
| Boling Point | 315.6±44.0 °C(Predicted) |
| Solubility | DMF: 50mg/mL |
| Appearance | powder |
| Color | White to Off-White |
| Storage Condition | -20°C |
| In vitro study | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
SIA - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| HS Code | 29251900 |
SIA - Reference Information
| biological activity | SIA Crosslinker is a non-cleavable ADC linker, it can be used to synthesize antibody-conjugated drugs (ADCS). |
| Use | a bifunctional crosslinker with amino and thiol reactivity. Typically, the coupling to a molecule containing a primary amine is initially through an amide bond buffered at pH 6.5 (8.5-7.0) followed by a pH 8.0 (-) the thioether chain under buffered conditions undergoes specific secondary bonding with a molecule containing a free thiol group. For the preparation of conjugates of enzyme immunocrosslinkers and hapten carrier molecules. A linker of two atoms is provided. |
Last Update：2024-04-09 02:00:10
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Spot supply
Product Name: Iodoacetic Acid N-Hydroxysuccinimide Ester Visit Supplier Webpage Request for quotationCAS: 39028-27-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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